Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | CPS1 | P31327 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1020456 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2APARP10BRD4BRPF1 | |
| SCHEMBL30829775 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2APARP10BRD4BRPF1 | |
| SCHEMBL11963662 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KMT2APARP10BRD4BRPF1 | |
| SCHEMBL2088803 | 0.77 | CYP1A2 (0.46) | ALDH1A1KMT2ACPS1KDM4EHSD17B10 | |
| SCHEMBL14949898 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2APARP10BRD4BRPF1 | |
| SCHEMBL3060647 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2APARP10BRD4BRPF1 | |
| SCHEMBL5018932 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2APARP10BRD4BRPF1 | |
| SCHEMBL4932356 | 0.76 | SLC6A4 (0.49) | ALDH1A1KMT2APARP10BRD4BRPF1 | |
| SCHEMBL6305238 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KMT2APARP10BRD4BRPF1 | |
| SCHEMBL8208073 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KMT2APARP10BRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139484-A1 | 1(Beta-D-Glycopyranosyl)-3-Substituted Nitrogenous Heterocyclic Compound, Medicinal Composition Containing the Same, and Medicinal Use Thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-06-12 | — | — | US | disclosed |
| EP-1803729-A1 | 1-( -D-GLYCOPYRANOSYL)-3-SUBSTITUTED NITROGENOUS HETEROCYCLIC COMPOUND, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139484-A1 | 1(Beta-D-Glycopyranosyl)-3-Substituted Nitrogenous Heterocyclic Compound, Medicinal Composition Containing the Same, and Medicinal Use Thereof | SLC5A1, SLC5A2, UGGT1 | ALDH1A1 853/4885KMT2A 862/4885PARP10 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.