Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921301 | 1.00 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1TSHREPHX2 | |
| SCHEMBL4932358 | 1.00 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1TSHREPHX2 | |
| SCHEMBL7794181 | 1.00 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1TSHREPHX2 | |
| SCHEMBL4932360 | 1.00 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1TSHREPHX2 | |
| SCHEMBL9062385 | 0.86 | KDM1A (0.48) | KDM1ARCOR1L3MBTL1TSHREPHX2 | |
| SCHEMBL9062391 | 0.86 | KDM1A (0.48) | KDM1ARCOR1L3MBTL1TSHREPHX2 | |
| SCHEMBL8835178 | 0.83 | KDM1A (0.39) | KDM1ARCOR1L3MBTL1TSHREPHX2 | |
| SCHEMBL9061313 | 0.82 | L3MBTL1 (0.45) | KDM1ARCOR1L3MBTL1TSHREPHX2 | |
| SCHEMBL6335424 | 0.82 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1TSHREPHX2 | |
| SCHEMBL3437339 | 0.82 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080173844-A1 | PHENYLCYCLOHEXANES AND A LIQUID-CRYSTALLINE MEDIUM | WACHTLER ANDREAS | 2008-07-24 | — | — | US | disclosed |
| US-7250199-B2 | Phenylcyclohexanes and a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2007-07-31 | — | — | US | disclosed |
| US-6955837-B2 | Phenylcyclohexanes and a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2005-10-18 | — | — | US | disclosed |
| US-20050133763-A1 | Phenylcyclohexanes and a liquid-crystalline medium | WACHTLER ANDREAS (DE) | 2005-06-23 | — | — | US | disclosed |
| US-20040169159-A9 | Phenylcyclohexanes and a liquid-crystalline medium | MERCK KGAA (DE) | 2004-09-02 | — | — | US | disclosed |
| US-20040089845-A1 | Phenylcyclohexanes and a liquid-crystalline medium | WACHTLER ANDREAS (DE) | 2004-05-13 | — | — | US | disclosed |
| US-6677002-B2 | FLUORO, OXYMETHYLDIFLUORO OR OXYMETHYLTRIFLUORO, CHLORO OR CYANO DERIVATIVES OF PHENYLCYCLOHEXANES AS COMPONENTS OF LIQUID CRYSTALLINE MEDIA FOR ELECTROOPTICAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-01-13 | — | — | US | disclosed |
| US-20020043646-A1 | Phenylcyclohexanes and a liquid-crystalline medium | MERCK KGAA (DE) | 2002-04-18 | — | — | US | disclosed |
| US-6284154-B1 | FOR LIQUID CRYSTAL CELLS, ELECTROPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-09-04 | — | — | US | disclosed |
| US-20010015422-A1 | Phenylcyclohexanes and a liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2001-08-23 | — | — | US | disclosed |
| US-5891360-A | ELECTROOPTICAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER (DE) | 1999-04-06 | — | — | US | disclosed |
| EP-0438563-B1 | PHENYLCYCLOHEXANES AND LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 1994-12-07 | — | — | EP | disclosed |
| WO-1991002709-A1 | PHENYLCYCLOHEXANES AND LIQUID CRYSTAL MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040089845-A1 | Phenylcyclohexanes and a liquid-crystalline medium | HCFC1, CYP2F1, CCR1 | KDM1A 3822/4885RCOR1 591/4885L3MBTL1 1108/4885 |
| US-20080173844-A1 | PHENYLCYCLOHEXANES AND A LIQUID-CRYSTALLINE MEDIUM | CYP2F1, CYP4F3, POF1B | KDM1A 3426/4885RCOR1 642/4885L3MBTL1 818/4885 |
| US-20020043646-A1 | Phenylcyclohexanes and a liquid-crystalline medium | CYP2F1, HCFC1, CYP4F11 | KDM1A 4021/4885RCOR1 547/4885L3MBTL1 1074/4885 |
| US-20040169159-A9 | Phenylcyclohexanes and a liquid-crystalline medium | CYP2F1, HCFC1, CYP4F11 | KDM1A 4021/4885RCOR1 547/4885L3MBTL1 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.