Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835312 | 0.96 | L3MBTL1 (0.40) | KDM1ARCOR1L3MBTL1EPHX2GRM2 | |
| SCHEMBL8835351 | 0.88 | L3MBTL1 (0.36) | KDM1ARCOR1L3MBTL1EPHX2ESR2 | |
| SCHEMBL8835310 | 0.85 | L3MBTL1 (0.34) | KDM1ARCOR1L3MBTL1EPHX2ESR2 | |
| SCHEMBL8835191 | 0.85 | L3MBTL1 (0.39) | KDM1ARCOR1L3MBTL1EPHX2ESR2 | |
| SCHEMBL4921301 | 0.83 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1EPHX2ESR2 | |
| SCHEMBL4929040 | 0.83 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1EPHX2ESR2 | |
| SCHEMBL4932360 | 0.83 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1EPHX2ESR2 | |
| SCHEMBL4932358 | 0.83 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1EPHX2ESR2 | |
| SCHEMBL7794181 | 0.83 | KDM1A (0.45) | KDM1ARCOR1L3MBTL1EPHX2ESR2 | |
| SCHEMBL8835194 | 0.82 | HTR2C (0.46) | KDM1ARCOR1ESR2GRM2TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0563982-A2 | Polycyclic diene derivatives | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |