Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RPA1 | P27694 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934207 | 0.92 | CYP1A2 (0.43) | CYP1A2HIF1APTGS2SMN1; SMN2MEN1 | |
| SCHEMBL4934205 | 0.92 | CYP1A2 (0.43) | CYP1A2HIF1APTGS2SMN1; SMN2MEN1 | |
| SCHEMBL1432255 | 0.92 | CYP1A2 (0.43) | CYP1A2HIF1APTGS2SMN1; SMN2MEN1 | |
| SCHEMBL4934058 | 0.86 | SMN1; SMN2 (0.55) | PTGS2SMN1; SMN2MEN1KMT2AKEAP1 | |
| SCHEMBL4933471 | 0.83 | ATM (0.43) | SMN1; SMN2KEAP1NFE2L2ATMNOTUM | |
| SCHEMBL4933764 | 0.81 | KMT2A (0.52) | SMN1; SMN2MEN1KMT2ANPSR1HPGD | |
| SCHEMBL4925543 | 0.81 | CNR2 (0.53) | MEN1KMT2ANPSR1USP2HPGD | |
| SCHEMBL1431678 | 0.79 | KEAP1 (0.49) | SMN1; SMN2HPGDKEAP1NFE2L2KDM4E | |
| SCHEMBL4927251 | 0.78 | PPARA (0.41) | SMN1; SMN2KEAP1NFE2L2PPARACA1 | |
| SCHEMBL4929226 | 0.78 | ALDH1A1 (0.48) | SMN1; SMN2MEN1KMT2AKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200501-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200501-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | CNR2, CNR1, OPRL1 | CYP1A2 3110/4885HIF1A 1318/4885PTGS2 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.