Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1754308 | 0.90 | AKR1C3 (0.58) | NPC1ALDH1A1SMN1; SMN2AKR1C3CDC25B | |
| Benzene SCHEMBL28318261 | 0.88 | AKR1C3 (0.61) | NPC1ALDH1A1SMN1; SMN2AKR1C3CDC25B | |
| SCHEMBL27873928 | 0.86 | AKR1C3 (0.65) | NPC1ALDH1A1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL4840898 | 0.84 | AGTR1 (0.47) | AGTR1NPC1KDM4EALDH1A1RAB9A | |
| SCHEMBL1466509 | 0.84 | AKR1C3 (0.68) | KDM4EALDH1A1AKR1C3CDC25BATM | |
| SCHEMBL10418498 | 0.82 | LIG1 (0.66) | NPC1ALDH1A1RAB9ASMN1; SMN2PKM | |
| SCHEMBL7849772 | 0.82 | LIG1 (0.66) | KDM4EALDH1A1RAB9APKMAKR1C3 | |
| SCHEMBL503678 | 0.82 | AKR1C3 (0.73) | KDM4EALDH1A1AKR1C3CDC25BATM | |
| SCHEMBL7850555 | 0.81 | AKR1C3 (0.48) | KDM4EALDH1A1AKR1C3CDC25BATM | |
| SCHEMBL2175941 | 0.81 | NR4A1 (0.70) | AGTR1NPC1KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103145580-B | Method for preparing 2-(4-fluorobenzene formyl) benzamide | YELLOW RIVER DELTA JINGBO RES INST CHEMICAL IND CO LTD | 2015-04-08 | — | — | CN | claimed |
| CN-103145580-B | Method for preparing 2-(4-fluorobenzene formyl) benzamide | YELLOW RIVER DELTA JINGBO RES INST CHEMICAL IND CO LTD | 2015-04-08 | — | — | CN | disclosed |
| CN-103145580-B | Method for preparing 2-(4-fluorobenzene formyl) benzamide | YELLOW RIVER DELTA JINGBO RES INST CHEMICAL IND CO LTD | 2015-04-08 | — | — | CN | disclosed |
| CN-103145580-B | Method for preparing 2-(4-fluorobenzene formyl) benzamide | YELLOW RIVER DELTA JINGBO RES INST CHEMICAL IND CO LTD | 2015-04-08 | — | — | CN | disclosed |
| CN-103086899-B | Synthesizing method of 2-amino-4'-fluoro-benzophenone | YELLOW RIVER DELTA JINGBO CHEMICAL RES INST CO LTD | 2014-09-17 | — | — | CN | disclosed |
| CN-103145580-A | Method for preparing 2-(4-fluorobenzene formyl) benzamide | YELLOW RIVER DELTA JINGBO CHEMICAL RES INST CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-103145580-A | Method for preparing 2-(4-fluorobenzene formyl) benzamide | YELLOW RIVER DELTA JINGBO CHEMICAL RES INST CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-103145580-A | Method for preparing 2-(4-fluorobenzene formyl) benzamide | YELLOW RIVER DELTA JINGBO CHEMICAL RES INST CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-103086899-A | Synthesizing method of 2-amino-4'-fluoro-benzophenone | YELLOW RIVER DELTA JINGBO CHEMICAL RES INST CO LTD | 2013-05-08 | — | — | CN | disclosed |
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
| CN-1690042-A | Preparation method of 2-amino-4' -fluoro-benzophenone | ZHUANG LUOYUAN (CN) | 2005-11-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | MCHR1, GPR119, MCHR2 | AGTR1 146/4885NPC1 472/4885KDM4E 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.