Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935053 | 0.92 | ALDH1A1 (0.40) | GAAKMT2ALMNAMAPTPOLB | |
| SCHEMBL4935045 | 0.92 | ALDH1A1 (0.40) | GAAKMT2ALMNAMAPTPOLB | |
| SCHEMBL4931860 | 0.90 | CCR5 (0.39) | GAAMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4931869 | 0.90 | CCR5 (0.39) | GAAMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4939039 | 0.88 | GAA (0.43) | GAAMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4939046 | 0.88 | GAA (0.43) | GAAMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4927314 | 0.88 | MEN1 (0.42) | MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL4927308 | 0.88 | MEN1 (0.42) | MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL4930360 | 0.81 | HDAC6 (0.41) | KMT2ALMNAMAPTPOLB | |
| SCHEMBL4930352 | 0.81 | HDAC6 (0.41) | KMT2ALMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | KUREHA CORPORATION (JP) | 2008-06-05 | — | — | US | disclosed |
| EP-1707560-A1 | HYDROXAMIC ACID DERIVATIVE AND AGE GENERATION INHIBITOR CONTAINING THE DERIVATIVE | Kureha Corporation (JP) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | HDAC5, HDAC1, HDAC9 | GAA 107/4885MEN1 3049/4885KMT2A 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.