Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4930620 | 1.00 | NPC1 (0.43) | NPC1RAB9ANOD2ALDH1A1HTT | |
| SCHEMBL4935914 | 0.83 | HDAC6 (0.47) | ALDH1A1HTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL4926554 | 0.83 | HDAC6 (0.47) | ALDH1A1HTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL4926564 | 0.83 | HDAC6 (0.47) | ALDH1A1HTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL4932791 | 0.82 | KMT2A (0.44) | NPC1RAB9ANOD2ALDH1A1KMT2A | |
| SCHEMBL4932797 | 0.82 | KMT2A (0.44) | NPC1RAB9ANOD2ALDH1A1KMT2A | |
| SCHEMBL4932173 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL4930609 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL4930600 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL4927847 | 0.77 | HTR6 (0.54) | ALDH1A1SMN1; SMN2KMT2AMAPTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | KUREHA CORPORATION (JP) | 2008-06-05 | — | — | US | disclosed |
| EP-1707560-A1 | HYDROXAMIC ACID DERIVATIVE AND AGE GENERATION INHIBITOR CONTAINING THE DERIVATIVE | Kureha Corporation (JP) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | HDAC5, HDAC1, HDAC9 | NPC1 2718/4885RAB9A 1921/4885NOD2 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.