Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566963 | 1.00 | LMNA (0.71) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL7565147 | 0.88 | TSHR (0.59) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL7574353 | 0.88 | TSHR (0.59) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL4881651 | 0.88 | TSHR (0.59) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL7566645 | 0.88 | TSHR (0.59) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL8935607 | 0.88 | TSHR (0.59) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL24226132 | 0.87 | LMNA (0.68) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL16653946 | 0.87 | LMNA (0.68) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL24226126 | 0.86 | LMNA (0.67) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL21097453 | 0.84 | POLB (0.79) | LMNAKMT2APOLBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335500-B2 | Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-02-26 | — | — | US | disclosed |
| US-20020068331-A1 | Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose | WONG CHI-HUEY (US) | 2002-06-06 | — | — | US | disclosed |
| US-6319695-B1 | FORMING A GLYCOSIDE BOND BY ETHERIFICATION AND CIRCULATION | THE SCRIPPS RESEARCH INSITUTE | 2001-11-20 | — | — | US | disclosed |