Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16653946 | 1.00 | LMNA (0.68) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL23031945 | 0.93 | LMNA (0.59) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL24226126 | 0.92 | LMNA (0.67) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL14268504 | 0.88 | TSHR (0.57) | LMNAKMT2APOLBALDH1A1CYP2C19 | |
| SCHEMBL7566963 | 0.87 | LMNA (0.71) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL4930970 | 0.87 | LMNA (0.71) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL8931476 | 0.86 | POLB (0.79) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL21097453 | 0.86 | POLB (0.79) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL8931470 | 0.86 | POLB (0.79) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL8668372 | 0.85 | LMNA (0.52) | LMNAKMT2APOLBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220025419-A1 | N-GLYCOSYLATION OF PEPTIDES AND PROTEINS | GLYCOVAXYN AG (CH) | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220025419-A1 | N-GLYCOSYLATION OF PEPTIDES AND PROTEINS | PGLS, NGLY1, PTMS | LMNA 1649/4885KMT2A 4219/4885POLB 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.