Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PER2 | O15055 | 1/20 | 0.30 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.30 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4930964 | 1.00 | MAP1LC3B (0.33) | MAP1LC3BHTR2ASLC6A2HTR2CSLC6A4 | |
| SCHEMBL13639649 | 0.76 | — | — | |
| SCHEMBL21338789 | 0.73 | MAP1LC3B (0.37) | MAP1LC3BHTR2AESR2HTR1ADRD2 | |
| SCHEMBL11308480 | 0.72 | ESR2 (0.41) | MAP1LC3BHTR2ASLC6A2HTR2CSLC6A4 | |
| SCHEMBL1066184 | 0.72 | KDM1A (0.48) | MAP1LC3BHTR2ASLC6A2HTR2CSLC6A4 | |
| SCHEMBL18161913 | 0.72 | KDM1A (0.48) | MAP1LC3BHTR2ASLC6A2HTR2CSLC6A4 | |
| SCHEMBL11498006 | 0.72 | ALDH1A1 (0.36) | MAP1LC3BHTR2ASLC6A2HTR2CSLC6A4 | |
| SCHEMBL22209655 | 0.70 | SLC18A3 (0.39) | MAP1LC3BHTR2ASLC6A2HTR2CSLC6A4 | |
| Ammonia Solution, Strong SCHEMBL22408764 | 0.70 | KDM1A (0.46) | MAP1LC3BHTR2ASLC6A2HTR2CSLC6A4 | |
| SCHEMBL9013796 | 0.70 | ESR2 (0.41) | HTR2AGRM2ESR2HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080173844-A1 | PHENYLCYCLOHEXANES AND A LIQUID-CRYSTALLINE MEDIUM | WACHTLER ANDREAS | 2008-07-24 | — | — | US | disclosed |
| US-7250199-B2 | Phenylcyclohexanes and a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2007-07-31 | — | — | US | disclosed |
| US-6955837-B2 | Phenylcyclohexanes and a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2005-10-18 | — | — | US | disclosed |
| US-20050133763-A1 | Phenylcyclohexanes and a liquid-crystalline medium | WACHTLER ANDREAS (DE) | 2005-06-23 | — | — | US | disclosed |
| US-20040089845-A1 | Phenylcyclohexanes and a liquid-crystalline medium | WACHTLER ANDREAS (DE) | 2004-05-13 | — | — | US | disclosed |
| US-6677002-B2 | FLUORO, OXYMETHYLDIFLUORO OR OXYMETHYLTRIFLUORO, CHLORO OR CYANO DERIVATIVES OF PHENYLCYCLOHEXANES AS COMPONENTS OF LIQUID CRYSTALLINE MEDIA FOR ELECTROOPTICAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-01-13 | — | — | US | disclosed |
| US-6284154-B1 | FOR LIQUID CRYSTAL CELLS, ELECTROPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-09-04 | — | — | US | disclosed |
| US-20010015422-A1 | Phenylcyclohexanes and a liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2001-08-23 | — | — | US | disclosed |
| US-5891360-A | ELECTROOPTICAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER (DE) | 1999-04-06 | — | — | US | disclosed |
| US-5458805-A | Phenylcyclohexanes and a liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-10-17 | — | — | US | disclosed |
| WO-1991002709-A1 | PHENYLCYCLOHEXANES AND LIQUID CRYSTAL MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040089845-A1 | Phenylcyclohexanes and a liquid-crystalline medium | HCFC1, CYP2F1, CCR1 | MAP1LC3B 2020/4885HTR2A 1623/4885SLC6A2 1921/4885 |
| US-20080173844-A1 | PHENYLCYCLOHEXANES AND A LIQUID-CRYSTALLINE MEDIUM | CYP2F1, CYP4F3, POF1B | MAP1LC3B 1655/4885HTR2A 1644/4885SLC6A2 3075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.