Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2833335 | 0.76 | IDH1 (0.36) | MAPTHTTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL4019944 | 0.76 | IDH1 (0.36) | MAPTHTTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL2833339 | 0.76 | IDH1 (0.36) | MAPTHTTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL4935623 | 0.73 | LMNA (0.42) | MAPTHTTL3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL6078838 | 0.72 | MAPT (0.34) | MAPTHTTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL4938646 | 0.72 | CNR1 (0.33) | LMNAJAK2 | |
| SCHEMBL4939489 | 0.71 | LMNA (0.33) | NPSR1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4025182 | 0.70 | ADORA2A (0.39) | MAPTHTTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL2546230 | 0.69 | ADORA2A (0.60) | HTTADORA2AKCNH2ADORA3ADORA2B | |
| SCHEMBL5164507 | 0.67 | NPC1 (0.34) | MAPK1ADORA2AADORA3ADORA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132522-A1 | 2-Substituted Pyrimidines, Method for Their Production and Their Use for Controlling Pathogenic Fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-05 | — | — | US | disclosed |
| EP-1768972-A1 | 2-SUBSTITUTED PYRIMIDINES, METHOD FOR THEIR PRODUCTION AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006005571-A1 | 2-SUBSTITUTED PYRIMIDINES, METHOD FOR THEIR PRODUCTION AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132522-A1 | 2-Substituted Pyrimidines, Method for Their Production and Their Use for Controlling Pathogenic Fungi | TYMS, TYMP, PNPO | MAPT 3172/4885HTT 3837/4885MAPK1 3695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.