Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826868 | 0.77 | GLP1R (0.42) | LMNASMN1; SMN2KDM4EMITFALDH1A1 | |
| SCHEMBL4935623 | 0.76 | LMNA (0.42) | LMNASMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL4938646 | 0.75 | CNR1 (0.33) | LMNAMAPK8MAPK9 | |
| SCHEMBL2833122 | 0.73 | KDM4E (0.33) | LMNASMN1; SMN2KDM4EMITFALDH1A1 | |
| SCHEMBL2833125 | 0.73 | KDM4E (0.33) | LMNASMN1; SMN2KDM4EMITFALDH1A1 | |
| SCHEMBL5164507 | 0.72 | NPC1 (0.34) | SMN1; SMN2RAB9A | |
| SCHEMBL5167350 | 0.72 | — | — | |
| SCHEMBL4932061 | 0.71 | MAPT (0.41) | LMNASMN1; SMN2KDM4EALDH1A1NPSR1 | |
| SCHEMBL6079376 | 0.70 | TLR8 (0.43) | PTGS1PTGS2 | |
| SCHEMBL4937597 | 0.69 | LMNA (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132522-A1 | 2-Substituted Pyrimidines, Method for Their Production and Their Use for Controlling Pathogenic Fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-05 | — | — | US | disclosed |
| EP-1768972-A1 | 2-SUBSTITUTED PYRIMIDINES, METHOD FOR THEIR PRODUCTION AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006005571-A1 | 2-SUBSTITUTED PYRIMIDINES, METHOD FOR THEIR PRODUCTION AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132522-A1 | 2-Substituted Pyrimidines, Method for Their Production and Their Use for Controlling Pathogenic Fungi | TYMS, TYMP, PNPO | LMNA 2500/4885SMN1; SMN2 1907/4885MAPK8 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.