Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931122 | 0.79 | KMT2A (0.43) | PTGER1LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3926276 | 0.76 | VNN1 (0.37) | PTGER1LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3934029 | 0.74 | DYRK1B (0.42) | CNR2CNR1ALDH1A1HPGDKDM4E | |
| SCHEMBL3928837 | 0.74 | GRM5 (0.41) | LMNACNR2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3927709 | 0.74 | MAOB (0.40) | PTGER1LMNACNR2CNR1ALDH1A1 | |
| SCHEMBL3925114 | 0.73 | KDM4E (0.40) | PTGER1LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3933545 | 0.73 | VNN1 (0.35) | PTGER1LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3929916 | 0.73 | DYRK1B (0.40) | TLR8CNR2ALDH1A1HPGDKDM4E | |
| SCHEMBL3929259 | 0.69 | KDR (0.39) | LMNAHPGDSMN1; SMN2MAPTCYP19A1 | |
| SCHEMBL3925118 | 0.68 | BRD4 (0.32) | LMNACNR2CNR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008059-A1 | ANTI-CANCER AGENTS ANS USES THEREOF | LOCUS PHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |