Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935814 | 0.83 | MAPT (0.52) | MAPTNPSR1ALDH1A1POLBHTT | |
| SCHEMBL11134071 | 0.80 | NPSR1 (0.49) | MAPTNPSR1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL4936202 | 0.79 | NPSR1 (0.70) | MAPTNPSR1ALDH1A1POLBHDAC3 | |
| SCHEMBL11667141 | 0.79 | POLB (0.49) | NPSR1ALDH1A1POLBGAAKMT2A | |
| SCHEMBL4929324 | 0.79 | NPSR1 (0.51) | MAPTNPSR1ALDH1A1POLBHDAC3 | |
| SCHEMBL4937216 | 0.78 | MEN1 (0.49) | MAPTNPSR1ALDH1A1POLBHTT | |
| SCHEMBL4932835 | 0.78 | KDM4E (0.53) | MAPTNPSR1ALDH1A1POLBHDAC3 | |
| Acrylic Acid SCHEMBL3955124 | 0.78 | MAPT (0.52) | MAPTNPSR1ALDH1A1POLBHDAC3 | |
| SCHEMBL2450680 | 0.76 | CYP1A2 (0.65) | MAPTNPSR1ALDH1A1POLBLMNA | |
| SCHEMBL7178423 | 0.76 | EGFR (0.52) | MAPTNPSR1ALDH1A1POLBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3259050-B1 | CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS | MERCK MILLIPORE LTD (IE) | 2020-06-10 | — | — | EP | claimed |
| US-9962691-B2 | Chromatography membranes formed by thiol-ene or thiol-yne click polymerization reactions | NATRIX SEPARATIONS INC. (CA) | 2018-05-08 | — | — | US | claimed |
| EP-3259050-A1 | CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS | Natrix Separations Inc. (CA) | 2017-12-27 | — | — | EP | claimed |
| WO-2016132224-A1 | CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS | NATRIX SEPARATIONS INC. (CA) | 2016-08-25 | — | — | WO | claimed |
| US-20160243538-A1 | Chromatography Membranes Formed by Thiol-Ene or Thiol-Yne Click Polymerization Reactions | MERCK MILLIPORE LTD. (IE) | 2016-08-25 | — | — | US | claimed |
| US-20080308492-A1 | Filter Medium for Technical Applications, and Method for the Production Thereof | MAHLE INTERNATIONAL GMBH (DE) | 2008-12-18 | — | — | US | claimed |
| US-11383229-B2 | Methods of separating substances from fluids | MERCK MILLIPORE LTD. (IE) | 2022-07-12 | — | — | US | disclosed |
| US-20210060541-A1 | METHODS OF SEPARATING SUBSTANCES FROM FLUIDS | MERCK MILLIPORE LTD. (IE) | 2021-03-04 | — | — | US | disclosed |
| EP-3778001-A1 | CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS | Merck Millipore Ltd. (IE) | 2021-02-17 | — | — | EP | disclosed |
| US-10864510-B2 | Methods of separating substances from fluids | MERCK MILLIPORE LTD. (IE) | 2020-12-15 | — | — | US | disclosed |
| EP-3259050-B1 | CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS | MERCK MILLIPORE LTD (IE) | 2020-06-10 | — | — | EP | disclosed |
| US-20200047175-A1 | CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS | MERCK MILLIPORE LTD. (IE) | 2020-02-13 | — | — | US | disclosed |
| US-10357766-B2 | Chromatography membranes formed by thiol-ene or thiol-yne click polymerization reactions | NATRIX SEPARATIONS INC. (CA) | 2019-07-23 | — | — | US | disclosed |
| US-20180297023-A1 | CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS | MERCK MILLIPORE LTD. (IE) | 2018-10-18 | — | — | US | disclosed |
| US-9962691-B2 | Chromatography membranes formed by thiol-ene or thiol-yne click polymerization reactions | NATRIX SEPARATIONS INC. (CA) | 2018-05-08 | — | — | US | disclosed |
| EP-3259050-A1 | CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS | Natrix Separations Inc. (CA) | 2017-12-27 | — | — | EP | disclosed |
| WO-2016132224-A1 | CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS | NATRIX SEPARATIONS INC. (CA) | 2016-08-25 | — | — | WO | disclosed |
| US-20160243538-A1 | Chromatography Membranes Formed by Thiol-Ene or Thiol-Yne Click Polymerization Reactions | MERCK MILLIPORE LTD. (IE) | 2016-08-25 | — | — | US | disclosed |
| US-20080308492-A1 | Filter Medium for Technical Applications, and Method for the Production Thereof | MAHLE INTERNATIONAL GMBH (DE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160243538-A1 | Chromatography Membranes Formed by Thiol-Ene or Thiol-Yne Click Polymerization Reactions | TST, TXN, GNE | MAPT 3505/4885NPSR1 1679/4885ALDH1A1 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.