Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933334 | 1.00 | ALDH1A1 (0.34) | ALDH1A1TUBB1GPR3 | |
| SCHEMBL29089985 | 0.85 | MAPK1 (0.32) | ALDH1A1GPR3 | |
| SCHEMBL12373121 | 0.85 | TSHR (0.33) | ALDH1A1GPR3 | |
| SCHEMBL29089982 | 0.85 | MAPK1 (0.32) | ALDH1A1GPR3 | |
| SCHEMBL15180598 | 0.85 | GPR3 (0.30) | GPR3 | |
| SCHEMBL14855284 | 0.85 | GPR3 (0.30) | GPR3 | |
| SCHEMBL15185153 | 0.85 | GPR3 (0.30) | GPR3 | |
| SCHEMBL29610667 | 0.85 | MAPK1 (0.32) | ALDH1A1GPR3 | |
| SCHEMBL14855286 | 0.85 | GPR3 (0.30) | GPR3 | |
| SCHEMBL24036549 | 0.83 | NPFFR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132536-A1 | PYRAZOLO [3,4-B] PYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS | GLAXO GROUP LIMITED | 2008-06-05 | — | — | US | disclosed |
| US-20070111995-A1 | Pyrazolo [3,4-B] pyridine Compounds and Their Use as Phosphodiesterase Inhibitors | GLAXO GROUP LIMITED (GB) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132536-A1 | PYRAZOLO [3,4-B] PYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS | PDE4A, PDE4B, PDE4C | ALDH1A1 842/4885TUBB1 3311/4885GPR3 290/4885 |
| US-20070111995-A1 | Pyrazolo [3,4-B] pyridine Compounds and Their Use as Phosphodiesterase Inhibitors | PDE4B, PDE3B, PDE4A | ALDH1A1 1120/4885TUBB1 3027/4885GPR3 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.