Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | MGLL | Q99685 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469796 | 0.96 | MEN1 (0.63) | MEN1KMT2AATMMGLLOPRM1 | |
| SCHEMBL6541617 | 0.91 | CA1 (0.58) | MEN1KMT2AATMMGLLOPRM1 | |
| Hydrochloric Acid SCHEMBL16507045 | 0.90 | CYP4A11 (0.57) | MEN1KMT2AATMMGLLOPRM1 | |
| SCHEMBL3746846 | 0.89 | SMN1; SMN2 (0.73) | MEN1KMT2AMGLLCA1CA2 | |
| Hydrochloric Acid SCHEMBL16506842 | 0.89 | SIGMAR1 (0.62) | MEN1KMT2AATMMGLLOPRM1 | |
| SCHEMBL15270421 | 0.88 | CA1 (0.64) | MEN1KMT2AATMMGLLOPRM1 | |
| Hydrochloric Acid SCHEMBL1169317 | 0.87 | SMN1; SMN2 (0.71) | MEN1KMT2AMGLLCA1CA2 | |
| SCHEMBL1928912 | 0.85 | TSHR (0.67) | MGLLCA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3310683 | 0.85 | LMNA (0.64) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL11846611 | 0.85 | CYP4F2 (0.64) | MEN1KMT2AATMMGLLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227295-B2 | Selective histone deactylase 6 inhibitors | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2019-03-12 | — | — | US | disclosed |
| US-20190010129-A1 | Amide derivatives as lysophosphatidic acid receptor antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2019-01-10 | — | — | US | disclosed |
| US-10100018-B2 | Amide derivatives as lysophosphatidic acid receptor antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-10-16 | — | — | US | disclosed |
| US-9956192-B2 | Selective histone deactylase 6 inhibitors | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170369428-A1 | SELECTIVE HISTONE DEACTYLASE 6 INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2017-12-28 | — | — | US | disclosed |
| US-9751832-B2 | Selective histone deactylase 6 inhibitors | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2017-09-05 | — | — | US | disclosed |
| US-9603889-B2 | IAP antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-28 | — | — | US | disclosed |
| US-9603889-B2 | IAP antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-28 | — | — | US | disclosed |
| EP-2903998-B1 | IAP ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-2903998-B1 | IAP ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2017-03-15 | — | — | EP | disclosed |
| WO-2014055461-A1 | IAP ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-04-10 | — | — | WO | disclosed |
| WO-2013134298-A1 | RAF INHIBITOR COMPOUNDS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2013-09-12 | — | — | WO | disclosed |
| WO-2013134467-A1 | SELECTIVE HISTONE DEACTYLASE 6 INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2013-09-12 | — | — | WO | disclosed |
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
| EP-1685094-A4 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S BIO PTE LTD (SG) | 2007-08-22 | — | — | EP | disclosed |
| EP-1685094-A1 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S*Bio Pte Ltd (SG) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005040101-A1 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | disclosed |
| WO-2005040101-A1 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10100018-B2 | Amide derivatives as lysophosphatidic acid receptor antagonists | LPAR1, LPAR2, LPAR3 | MEN1 1217/4885KMT2A 585/4885ATM 3506/4885 |
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | HDAC1, HDAC3, HDAC4 | MEN1 2737/4885KMT2A 105/4885ATM 3912/4885 |
| US-20190010129-A1 | Amide derivatives as lysophosphatidic acid receptor antagonists | LPAR1, LPAR2, LPAR3 | MEN1 1195/4885KMT2A 593/4885ATM 3500/4885 |
| US-20170369428-A1 | SELECTIVE HISTONE DEACTYLASE 6 INHIBITORS | HDAC1, HDAC5, HDAC11 | MEN1 2363/4885KMT2A 48/4885ATM 1999/4885 |
| US-10227295-B2 | Selective histone deactylase 6 inhibitors | HDAC1, HDAC5, HDAC11 | MEN1 2363/4885KMT2A 48/4885ATM 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.