Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Thiourea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL30121260 | 1.00 | TSHR (0.75) | — | |
| Thiourea SCHEMBL10390991 | 0.88 | — | — | |
| Thiourea SCHEMBL2232139 | 0.88 | — | — | |
| Thiourea SCHEMBL28878007 | 0.88 | — | — | |
| Thiourea SCHEMBL15353197 | 0.88 | TSHR (0.75) | — | |
| Thiourea SCHEMBL15353245 | 0.88 | TSHR (0.75) | — | |
| Thiourea SCHEMBL15353549 | 0.88 | TSHR (0.75) | — | |
| Thiourea SCHEMBL7593798 | 0.88 | — | — | |
| Thiourea SCHEMBL17728202 | 0.88 | TSHR (0.75) | — | |
| Thiourea SCHEMBL850383 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880413-B1 | METHOD OF PREPARING ZINC OXIDE NANORODS ON A SUBSTRATE BY CHEMICAL SPRAY PYROLYSIS | TALLINN UNIV OF TECH (EE) | 2017-10-18 | — | — | EP | disclosed |
| US-8808801-B2 | Method of preparing zinc oxide nanorods on a substrate by chemical spray pyrolysis | NANOSOL ENERGY OÜ (EE) | 2014-08-19 | — | — | US | disclosed |
| US-20130236646-A1 | METHOD OF PREPARING ZINC OXIDE NANORODS ON A SUBSTRATE BY CHEMICAL SPRAY PYROLYSIS | NANOSOL ENERGY OÜ (EE) | 2013-09-12 | — | — | US | disclosed |
| US-20080280058-A1 | Aqueous or aqueous alcoholic solution comprising zinc chloride or zinc acetate as precursors is sprayed onto preheated substrate so that precursor reacts to form zinc oxide layer on substrate; thiourea or urea may be added; cheap and simple method; solar cells, field emission devices, sensors | TALLINN UNIVERSITY OF TECHNOLOGY (EE) | 2008-11-13 | — | — | US | disclosed |
| EP-1880413-A1 | METHOD OF PREPARING ZINC OXIDE NANORODS ON A SUBSTRATE BY CHEMICAL SPRAY PYROLYSIS | Tallinn University of Technology (EE) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108425-A1 | METHOD OF PREPARING ZINC OXIDE NANORODS ON A SUBSTRATE BY CHEMICAL SPRAY PYROLYSIS | TALLINN UNIVERSITY OF TECHNOLOGY (EE) | 2006-10-19 | — | — | WO | disclosed |