Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4930739 | 0.81 | KMT2A (0.34) | PTGDR2 | |
| SCHEMBL4930821 | 0.77 | NPC1 (0.32) | — | |
| SCHEMBL4933608 | 0.70 | CDK4 (0.34) | KHK | |
| SCHEMBL12604362 | 0.67 | KMT2A (0.49) | — | |
| SCHEMBL1472484 | 0.67 | KMT2A (0.55) | — | |
| SCHEMBL4011568 | 0.65 | FABP4 (0.42) | — | |
| SCHEMBL4330507 | 0.65 | PDE4B (0.41) | — | |
| SCHEMBL4938911 | 0.64 | PPARA (0.37) | KHK | |
| SCHEMBL7689618 | 0.62 | ADORA3 (0.45) | — | |
| SCHEMBL31194557 | 0.62 | CDK4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021058-A1 | Pyrazolo '3,4-B! Pyridine Compounds And Their Use As Phosphodiesterase Type 4(Pde4) Inhibitors | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021058-A1 | Pyrazolo '3,4-B! Pyridine Compounds And Their Use As Phosphodiesterase Type 4(Pde4) Inhibitors | PDE4A, PDE4B, PDE3B | PTGDR2 587/4885KHK 1526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.