SCHEMBL493426

SCHEMBL493426

CC(=O)[C@H](S)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.33
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3792332 1.00 MGLL (0.33) MGLLGLA
SCHEMBL18540883 0.81 MGLL (0.34) MGLL
SCHEMBL863100 0.79 MGLL (0.33) MGLLGLA
SCHEMBL1541732 0.79 MGLL (0.33) MGLLGLA
SCHEMBL2146991 0.77 MGLL (0.34) MGLL
SCHEMBL17430432 0.76 MGLL (0.36) MGLLGLA
SCHEMBL258692 0.76 MGLL (0.36) MGLLGLA
SCHEMBL18908274 0.75 MGLL (0.35) MGLLGLA
SCHEMBL13551294 0.75 MGLL (0.35) MGLLGLA
SCHEMBL18908216 0.74 GLA (0.34) MGLLGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1701950-B1 ECSTASY HAPTENS AND IMMUNOGENS SIEMENS HEALTHCARE DIAGNOSTICS (US) 2014-02-12 EP disclosed
US-20120039843-A1 CONJUGATES OF A POLYPEPTIDE AND AN OLIGOSACCHARIDE N.V. ORGANON (NL) 2012-02-16 US disclosed
US-8106007-B2 Having affinity to antithrombin III; improved pharmacokinetic properties when compared to the original polypeptides N.V. ORGANON (NL) 2012-01-31 US disclosed
US-7863427-B2 Immunoassays for buprenorphine and norbuprenorphine SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2011-01-04 US disclosed
EP-2264464-A2 Immunoassays for buprenorphine and norbuprenorphine Siemens Healthcare Diagnostics Inc. (US) 2010-12-22 EP disclosed
EP-1701950-A4 ECSTASY HAPTENS AND IMMUNOGENS SIEMENS HEALTHCARE DIAGNOSTICS (US) 2009-03-04 EP disclosed
US-20080268453-A1 Types of lymphoma and method for prognosis thereof AICHI PREFECTURE (JP) 2008-10-30 US disclosed
EP-1976563-A2 CONJUGATES OF A POLYPEPTIDE AND AN OLIGOSACCHARIDE N.V. Organon (NL) 2008-10-08 EP disclosed
US-20080139459-A1 Conjugates A Polypeptide And A Pentasaccharide N.V. ORGANON (NL) 2008-06-12 US disclosed
EP-1756570-A4 IMMUNOASSAYS FOR BUPRENORPHINE AND NORBUPRENORPHINE DADE BEHRING INC (US) 2008-05-21 EP disclosed
WO-2005103697-A2 IMMUNOASSAYS FOR BUPRENORPHINE AND NORBUPRENORPHINE DADE BEHRING INC. (US) 2005-11-03 WO disclosed
US-20050221405-A1 Immunoassays for buprenorphine and norbuprenorphine SIEMENS HEALTHCARE DIAGNOSTICS INC. 2005-10-06 US disclosed
WO-2005061482-A1 ECSTASY HAPTENS AND IMMUNOGENS DADE BEHRING INC. (US) 2005-07-07 WO disclosed
US-20050130225-A1 Ecstasy haptens and immunogens SIEMENS HEALTHCARE DIAGNOSTICS INC. 2005-06-16 US disclosed
US-20040214171-A1 Cat kidney disease marker TOHOKU TECHNO ARCH CO., LTD. 2004-10-28 US disclosed
EP-0540612-A1 HETEROBIFUNCTIONAL REAGENTS AND CONJUGATES WITH OXAALKYLENE UNITS FOR AMPHIPHILIC BRIDGE STRUCTURES Pharmacia AB (SE) 1993-05-12 EP disclosed
EP-0276516-B1 NEW OLIGOSACCHARIDES, IMMUNOGENS AND VACCINES, AND METHODS FOR PREPARING SUCH OLIGOSACCHARIDES, IMMUNOGENS AND VACCINES De Staat der Nederlanden, represented by the Deputy Director-General of the RIVM of Bilthoven (NL) 1993-03-17 EP disclosed
WO-1992001474-A1 HETEROBIFUNCTIONAL REAGENTS AND CONJUGATES WITH OXAALKYLENE UNITS FOR AMPHIPHILIC BRIDGE STRUCTURES KABI PHARMACIA AB (SE) 1992-02-06 WO disclosed
US-5034519-A Ribose, ribitol and phosphate oligosaccharides for vaccines and immunology for haemophilus DE STAAT DER NEDERLANDEN (NL) 1991-07-23 US disclosed
EP-0276516-A2 New oligosaccharides, immunogens and vaccines, and methods for preparing such oligosaccharides, immunogens and vaccines De Staat der Nederlanden, represented by the Deputy Director-General of the RIVM of Bilthoven (NL) 1988-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139459-A1 Conjugates A Polypeptide And A Pentasaccharide SERPINC1, F13A1, F13B MGLL 4446/4885GLA 2087/4885
US-20120039843-A1 CONJUGATES OF A POLYPEPTIDE AND AN OLIGOSACCHARIDE SERPINC1, SELP, F13B MGLL 4425/4885GLA 1874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.