Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | XPO1 | O14980 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931542 | 0.87 | ALDH1A1 (0.54) | MAPTL3MBTL1SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL1432107 | 0.85 | KMT2A (0.50) | MAPTALDH1A1SMN1; SMN2CA9LMNA | |
| SCHEMBL1431633 | 0.85 | ALDH1A1 (0.49) | MAPTL3MBTL1SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL1432291 | 0.85 | SLC5A1 (0.45) | MAPTSLC5A1SLC5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL1431635 | 0.85 | ALOX12 (0.54) | MAPTHTTADORA1SLC5A1SLC5A2 | |
| SCHEMBL4933169 | 0.84 | SMN1; SMN2 (0.52) | MAPTL3MBTL1ADORA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4933802 | 0.84 | KDM4E (0.46) | MAPTHTTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4935386 | 0.83 | ADORA1 (0.49) | MAPTADORA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1432032 | 0.80 | NOTUM (0.45) | MAPTHTTALDH1A1CASP3 | |
| SCHEMBL4925541 | 0.80 | CNR2 (0.58) | MAPTHTTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200501-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200501-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | CNR2, CNR1, OPRL1 | MAPT 665/4885HTT 465/4885L3MBTL1 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.