SCHEMBL493442

SCHEMBL493442

COc1ccc(C=O)cc1C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.70
TSHR P16473 1/20 0.70
AOX1 Q06278 1/20 0.63
FDPS P14324 1/20 0.59
HPGD P15428 2/20 0.58
TRIM24 O15164 1/20 0.58
ALDH5A1 P51649 1/20 0.58
ABAT P80404 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
TRIM33 Q9UPN9 1/20 0.58
TTR P02766 1/20 0.54
ALDH1A3 P47895 1/20 0.49
CYP2A6 P11509 1/20 0.48
MAPT P10636 5/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TUBB1 Q9H4B7 4/20 0.47
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7534312 0.87 NQO2 (0.58) ALDH1A1TSHRAOX1FDPSHPGD
SCHEMBL23327885 0.87 ALDH1A1 (0.54) ALDH1A1TSHRAOX1FDPSHPGD
SCHEMBL26982552 0.86 ALDH1A1 (0.63) ALDH1A1TSHRAOX1FDPSHPGD
SCHEMBL15580939 0.86 ALDH1A1 (0.53) ALDH1A1TSHRAOX1FDPSHPGD
Glycine SCHEMBL8218503 0.85 ALDH1A1 (0.53) ALDH1A1TSHRAOX1FDPSHPGD
SCHEMBL7530242 0.85 ALDH1A1 (0.53) ALDH1A1TSHRAOX1FDPSHPGD
SCHEMBL8702746 0.85 ALDH1A1 (0.53) ALDH1A1TSHRAOX1FDPSHPGD
SCHEMBL19849522 0.85 ALDH1A1 (0.55) ALDH1A1TSHRAOX1FDPSHPGD
SCHEMBL18640078 0.85 ALDH1A1 (0.56) ALDH1A1TSHRAOX1FDPSHPGD
SCHEMBL23043 0.83 ALDH1A1 (0.70) ALDH1A1TSHRAOX1FDPSHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 671 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137586-A2 COMPOSITIONS, METHODS, AND SYSTEMS FOR PROMOTING PHOSPHATE SOLUBILIZATION IN PLANTS Tenfold Technologies, LLC (US) 2025-06-26 WO claimed
US-20230404887-A1 COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF SWEAT MALODOR FIRMENICH SA (CH) 2023-12-21 US claimed
CN-117024304-A Preparation method of N ', N' -diaryl hydrazide compound 赣南师范大学 2023-11-10 CN claimed
CN-114981247-A Piperazine compounds for inhibiting CPS1 卫材R&D管理有限公司 2022-08-30 CN claimed
CN-114173750-A Improving the stability of agents for treating keratin materials 汉高股份有限及两合公司 2022-03-11 CN claimed
EP-2199290-B1 Method of nucleating a polyolefin composition with acetal-based compounds MILLIKEN & CO (US) 2018-06-06 EP claimed
CN-104649879-B Substituted benzene methylene 1,2,3,4-Tetrahydrooxonaphthalene analog derivative and preparation method, application 中国人民解放军第二军医大学 2017-01-04 CN claimed
EP-2663542-B1 PROCESS FOR THE PREPARATION OF ALDITOL ACETALS RELIANCE IND LTD (IN) 2016-07-06 EP claimed
CN-104649879-A Substituted benzylidene tetralone derivatives and preparation method and applications UNIV PLA 2ND MILITARY MEDICAL 2015-05-27 CN claimed
US-9029575-B2 Process for preparation of acetals RELIANCE INDUSTRIES LIMITED (IN) 2015-05-12 US claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
WO-2005111134-A2 METHOD OF NUCLEATING A POLYOLEFIN COMPOSITION WITH ACETAL-BASED COMPOUNDS MILLIKEN & COMPANY (US) 2005-11-24 WO claimed
WO-2005108479-A2 ACETAL-BASED COMPOSITIONS MILLIKEN & COMPANY (US) 2005-11-17 WO claimed
US-20050239928-A1 Acetal-based compositions MILLIKEN & COMPANY 2005-10-27 US claimed
US-20050239926-A1 Method of nucleating a polyolefin composition with acetal-based compounds MILLIKEN & COMPANY 2005-10-27 US claimed
WO-2001001977-A1 METHODS FOR CONTROLLING FUNGAL PATHOGENS SUMMUS GROUP LTD. (US) 2001-01-11 WO claimed
EP-0151593-B1 ENZYME DERIVATIVES BEECHAM GROUP PLC (GB) 1989-02-22 EP claimed
US-4604285-A ANTICOAGULANT BEECHAM GROUP P.L.C. (GB) 1986-08-05 US claimed
EP-0151593-A1 ENZYME DERIVATIVES. BEECHAM GROUP PLC (GB) 1985-08-21 EP claimed
WO-1985000521-A1 ENZYME DERIVATIVES BEECHAM GROUP P.L.C. (GB) 1985-02-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239928-A1 Acetal-based compositions PCNA, RAD51, AR ALDH1A1 575/4885TSHR 4626/4885AOX1 1051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.