SCHEMBL4934712

SCHEMBL4934712

CCC(CN(C)C)Oc1c(Cl)cc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3-c3ccccc3)CC2)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 16/20 0.54
GPR55 Q9Y2T6 4/20 0.45
CNR1 P21554 2/20 0.41
KCNH2 Q12809 1/20 0.39
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4939243 0.84 SLC6A9 (0.57) SLC6A9GPR55CNR1TSHR
SCHEMBL4934622 0.83 SLC6A9 (0.56) SLC6A9GPR55CNR1TSHR
SCHEMBL4936345 0.83 SLC6A9 (0.65) SLC6A9GPR55KCNH2TSHR
SCHEMBL14028685 0.83 SLC6A9 (0.56) SLC6A9GPR55CNR1TSHR
SCHEMBL4948280 0.80 SLC6A9 (0.68) SLC6A9GPR55CNR1TSHR
SCHEMBL4943081 0.79 SLC6A9 (0.57) SLC6A9GPR55CNR1
SCHEMBL4937577 0.79 SLC6A9 (0.71) SLC6A9GPR55TSHR
SCHEMBL4434158 0.77 SLC6A9 (0.80) SLC6A9GPR55CNR1TSHR
SCHEMBL4943129 0.76 SLC6A9 (0.67) SLC6A9GPR55KCNH2TSHR
SCHEMBL4424927 0.75 SLC6A9 (0.74) SLC6A9GPR55CNR1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255144-A1 Acylated Piperidines as Glycine Transporter Inhibitors GLAXO GROUP LIMITED 2008-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080255144-A1 Acylated Piperidines as Glycine Transporter Inhibitors SLC1A1, SLC6A7, SLC1A2 SLC6A9 9/4885GPR55 485/4885CNR1 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.