Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.48 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.48 |
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4938989 | 0.98 | L3MBTL3 (0.64) | L3MBTL3L3MBTL1HRH3ACHECYP2D6 | |
| SCHEMBL4935057 | 0.88 | HRH3 (0.54) | L3MBTL3L3MBTL1HRH3ACHEKDM4E | |
| SCHEMBL4931385 | 0.86 | L3MBTL3 (0.68) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL4936788 | 0.84 | L3MBTL3 (0.66) | L3MBTL3L3MBTL1HRH3CYP2D6MBTD1 | |
| SCHEMBL6206248 | 0.84 | L3MBTL3 (0.66) | L3MBTL3L3MBTL1HRH3MBTD1TP53BP1 | |
| SCHEMBL4937869 | 0.84 | L3MBTL3 (0.66) | L3MBTL3L3MBTL1HRH3CYP2D6MBTD1 | |
| SCHEMBL4931707 | 0.84 | L3MBTL3 (0.66) | L3MBTL3L3MBTL1HRH3CYP2D6MBTD1 | |
| SCHEMBL4937880 | 0.84 | L3MBTL3 (0.66) | L3MBTL3L3MBTL1HRH3CYP2D6MBTD1 | |
| SCHEMBL4941296 | 0.84 | L3MBTL3 (0.66) | L3MBTL3L3MBTL1HRH3CYP2D6MBTD1 | |
| SCHEMBL4940259 | 0.81 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1HRH3ACHECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004314-A1 | Phenylpiperidines and Phenylpyrrolidines | APODACA RICHARD L | 2008-01-03 | — | — | US | disclosed |
| US-20080004314-A1 | Phenylpiperidines and Phenylpyrrolidines | APODACA RICHARD L | 2008-01-03 | — | — | US | disclosed |
| US-20080004314-A1 | Phenylpiperidines and Phenylpyrrolidines | APODACA RICHARD L | 2008-01-03 | — | — | US | disclosed |
| US-7279491-B2 | Phenylpiperidines and phenylpyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-09 | — | — | US | disclosed |
| US-7279491-B2 | Phenylpiperidines and phenylpyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-09 | — | — | US | disclosed |
| US-7279491-B2 | Phenylpiperidines and phenylpyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-09 | — | — | US | disclosed |
| US-20040087573-A1 | Phenylpiperidines and phenylpyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087573-A1 | Phenylpiperidines and phenylpyrrolidines | HRH2, HNMT, HRH3 | L3MBTL3 4833/4885L3MBTL1 4814/4885HRH3 3/4885 |
| US-20080004314-A1 | Phenylpiperidines and Phenylpyrrolidines | HRH2, HNMT, HRH3 | L3MBTL3 4833/4885L3MBTL1 4814/4885HRH3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.