Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935449 | 1.00 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4935380 | 0.91 | HDAC1 (0.58) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL24322687 | 0.90 | SMN1; SMN2 (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL1768546 | 0.84 | SMN1; SMN2 (0.61) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL1768548 | 0.84 | SMN1; SMN2 (0.61) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL1768585 | 0.82 | SMN1; SMN2 (0.59) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL1768587 | 0.82 | SMN1; SMN2 (0.59) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL10132091 | 0.82 | LMNA (0.56) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL10885389 | 0.78 | BLM (0.52) | SMN1; SMN2ALDH1A1HPGDCASREPHX1 | |
| SCHEMBL10885385 | 0.78 | BLM (0.52) | SMN1; SMN2ALDH1A1HPGDCASREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | KUREHA CORPORATION (JP) | 2008-06-05 | — | — | US | disclosed |
| EP-1707560-A1 | HYDROXAMIC ACID DERIVATIVE AND AGE GENERATION INHIBITOR CONTAINING THE DERIVATIVE | Kureha Corporation (JP) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | HDAC5, HDAC1, HDAC9 | HDAC3 17/4885HDAC1 2/4885HDAC2 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.