Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11406503 | 1.00 | BLM (0.52) | BLMLMNADPP4DPP8DPP9 | |
| SCHEMBL10885389 | 1.00 | BLM (0.52) | BLMLMNADPP4DPP8DPP9 | |
| SCHEMBL30799584 | 0.91 | BLM (0.56) | BLMLMNADPP4DPP8DPP9 | |
| SCHEMBL24322687 | 0.87 | SMN1; SMN2 (0.55) | BLMLMNADPP4DPP8EPHX1 | |
| SCHEMBL10886863 | 0.83 | EPHX1 (0.45) | BLMLMNAEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL10889695 | 0.83 | EPHX1 (0.45) | BLMLMNAEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL28337863 | 0.80 | CPB2 (0.49) | BLMLMNADPP4DPP8DPP9 | |
| SCHEMBL3592432 | 0.80 | CPB2 (0.49) | BLMLMNADPP4DPP8DPP9 | |
| SCHEMBL8450554 | 0.79 | LMNA (0.48) | BLMLMNAEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL18459934 | 0.79 | EPHX1 (0.48) | BLMLMNAEPHX1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078152-B1 | SALTS OF SULFODEHYDROABIETIC ACID AND TREATMENT OF GASTRO-INTESTINAL DISEASES | Tanabe Seiyaku Co., Ltd. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4529602-A | Sulfodehydroabietic acid compound | TANABE SEIYAKU CO., LTD. (JP) | 1985-07-16 | — | — | US | disclosed |
| EP-0078152-A1 | Salts of sulfodehydroabietic acid and treatment of gastro-intestinal diseases | Tanabe Seiyaku Co., Ltd. (JP) | 1983-05-04 | — | — | EP | disclosed |