Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 5/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.50 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230561 | 0.93 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1HPGD | |
| SCHEMBL11229197 | 0.82 | ERN1 (0.54) | ALDH1A1KDM4ETDP1HPGDHSD17B10 | |
| SCHEMBL4059355 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4ETSHRTDP1HPGD | |
| SCHEMBL8393507 | 0.79 | NQO1 (0.67) | ALDH1A1KDM4EHPGDHSD17B10NQO1 | |
| SCHEMBL29919905 | 0.79 | NQO1 (0.67) | ALDH1A1KDM4EHPGDHSD17B10NQO1 | |
| SCHEMBL24250199 | 0.79 | ERN1 (0.54) | ALDH1A1KDM4ETSHRTDP1HPGD | |
| SCHEMBL11299778 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRTDP1HPGD | |
| SCHEMBL1487621 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KDM4ETSHRTDP1HPGD | |
| SCHEMBL8391116 | 0.77 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10NQO1 | |
| SCHEMBL29862025 | 0.77 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242585-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230242585-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-03 | — | — | US | disclosed |
| WO-2021226460-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-11-11 | — | — | WO | disclosed |
| CN-101883785-B | New non-selective somatostatin analogues | ITALFARMACO SPA | 2014-01-15 | — | — | CN | disclosed |
| CN-101883785-A | New non-selective somatostatin analogues | ITALFARMACO SPA | 2010-11-10 | — | — | CN | disclosed |
| US-20080287399-A1 | Substituted Aminopyridines and Uses Thereof | ASTRAZENECA AB (SE) | 2008-11-20 | — | — | US | disclosed |
| CN-101124205-A | Substituted aminopyridines and uses thereof | ASTRAZENECA AB (SE) | 2008-02-13 | — | — | CN | disclosed |
| EP-1831170-A1 | SUBSTITUTED AMINOPYRIDINES AND USES THEREOF | AstraZeneca AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006065204-A1 | SUBSTITUTED AMINOPYRIDINES AND USES THEREOF | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287399-A1 | Substituted Aminopyridines and Uses Thereof | PSEN2, SLC1A2, PSEN1 | ALDH1A1 1429/4885KDM4E 2474/4885TSHR 4728/4885 |
| US-20230242585-A1 | IMMUNOMODULATORS | CD274, PDCD1, PDCD1LG2 | ALDH1A1 3370/4885KDM4E 2092/4885TSHR 1228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.