SCHEMBL4935527

SCHEMBL4935527

C=CCN(CC=C)C(=O)Nc1cccc(Cl)c1Cl

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.55
KMT2A Q03164 9/20 0.55
ALDH1A1 P00352 2/20 0.52
NPSR1 Q6W5P4 1/20 0.47
MAPT P10636 5/20 0.47
LMNA P02545 3/20 0.47
MAPK1 P28482 1/20 0.46
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 1/20 0.43
PDK1 Q15118 1/20 0.43
PDK2 Q15119 1/20 0.43
PDK3 Q15120 1/20 0.43
PDK4 Q16654 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4937768 0.83 ALDH1A1 (0.49) MEN1KMT2AALDH1A1NPSR1MAPT
SCHEMBL4929324 0.78 NPSR1 (0.51) ALDH1A1NPSR1MAPTLMNANPC1
SCHEMBL4935865 0.77 ALDH1A1 (0.56) MEN1KMT2AALDH1A1NPSR1MAPT
SCHEMBL4933165 0.77 ALDH1A1 (0.66) MEN1KMT2AALDH1A1NPSR1MAPT
SCHEMBL4938466 0.77 ALDH1A1 (0.70) MEN1KMT2AALDH1A1NPSR1MAPT
SCHEMBL4932835 0.77 KDM4E (0.53) MEN1KMT2AALDH1A1NPSR1MAPT
SCHEMBL11134071 0.76 NPSR1 (0.49) ALDH1A1NPSR1MAPTMAPK1NPC1
SCHEMBL4933159 0.75 MAPT (0.51) MEN1KMT2AALDH1A1NPSR1MAPT
SCHEMBL30441009 0.74 MEN1 (0.61) MEN1KMT2AALDH1A1MAPTLMNA
SCHEMBL465871 0.74 MEN1 (0.61) MEN1KMT2AALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080308492-A1 Filter Medium for Technical Applications, and Method for the Production Thereof MAHLE INTERNATIONAL GMBH (DE) 2008-12-18 US claimed
US-20080308492-A1 Filter Medium for Technical Applications, and Method for the Production Thereof MAHLE INTERNATIONAL GMBH (DE) 2008-12-18 US disclosed