⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27938332 | 0.74 | — | — | |
| SCHEMBL20187650 | 0.74 | — | — | |
| SCHEMBL29017099 | 0.71 | — | — | |
| SCHEMBL5229482 | 0.71 | TDP1 (0.42) | — | |
| Isopropyl Alcohol SCHEMBL7739794 | 0.71 | — | — | |
| SCHEMBL3927423 | 0.69 | — | — | |
| SCHEMBL20508958 | 0.67 | ALDH1A1 (0.43) | — | |
| Propylene Glycol SCHEMBL10422544 | 0.65 | — | — | |
| SCHEMBL9572897 | 0.64 | — | — | |
| SCHEMBL18421719 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298011-B1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA INC (US) | 2021-11-17 | — | — | EP | claimed |
| US-20180155340-A1 | QUINOLONE DERIVATIVES AS FGFR INHIBITORS | PRINCIPIA BIOPHARMA INC. | 2018-06-07 | — | — | US | claimed |
| US-20070015792-A1 | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | MSD K.K. (JP) | 2007-01-18 | — | — | US | claimed |
| CN-101223158-B | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | BANYU PHARMA CO LTD | 2013-01-09 | — | — | CN | disclosed |
| CN-101223158-A | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | BANYU PHARMA CO LTD (JP) | 2008-07-16 | — | — | CN | disclosed |
| US-20080103178-A1 | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | MSD K.K. (JP) | 2008-05-01 | — | — | US | disclosed |
| US-20070015792-A1 | N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives | MSD K.K. (JP) | 2007-01-18 | — | — | US | disclosed |