Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935784 | 1.00 | TLR4 (0.54) | TLR4TLR2CHEK2NFE2L2TLR9 | |
| SCHEMBL3247265 | 0.87 | NFE2L2 (0.63) | NFE2L2CYP19A1ALDH1A1MEN1MAPT | |
| SCHEMBL3247258 | 0.87 | NFE2L2 (0.63) | NFE2L2CYP19A1ALDH1A1MEN1MAPT | |
| SCHEMBL3248830 | 0.84 | BACE1 (0.54) | TLR4TLR2ALDH1A1MEN1MAPT | |
| SCHEMBL3248827 | 0.84 | BACE1 (0.54) | TLR4TLR2ALDH1A1MEN1MAPT | |
| SCHEMBL567173 | 0.84 | NFE2L2 (0.64) | NFE2L2TLR9CYP19A1ALDH1A1MAPT | |
| SCHEMBL567172 | 0.84 | NFE2L2 (0.64) | NFE2L2TLR9CYP19A1ALDH1A1MAPT | |
| SCHEMBL34473878 | 0.83 | PELI1 (0.53) | TLR4TLR2CHEK2NFE2L2TLR9 | |
| SCHEMBL13767769 | 0.80 | ALDH1A1 (0.60) | CYP19A1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL3248725 | 0.79 | NFE2L2 (0.61) | NFE2L2TLR9CYP19A1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085455-A1 | Methods for storing holographic data and storage media derived therefrom | GENERAL ELECTRIC COMPANY (US) | 2008-04-10 | — | — | US | disclosed |