SCHEMBL4935995

SCHEMBL4935995

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.42
OPRD1 P41143 3/20 0.42
BACE1 P56817 3/20 0.36
MME P08473 1/20 0.36
ERAP2 Q6P179 3/20 0.35
CTSD P07339 2/20 0.35
CTSB P07858 1/20 0.35
IL1RN P18510 2/20 0.34
ERAP1 Q9NZ08 2/20 0.34
REN P00797 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5526723 1.00 OPRM1 (0.42) OPRM1OPRD1BACE1MMEERAP2
Threonine SCHEMBL28512021 0.91 MME (0.38) BACE1MMEERAP2IL1RNERAP1
SCHEMBL29530913 0.91 MME (0.40) OPRM1OPRD1MME
SCHEMBL3750892 0.90 MME (0.41) MME
SCHEMBL3750881 0.90 MME (0.41) MME
SCHEMBL30658572 0.90 ERAP2 (0.40) BACE1MMEERAP2IL1RNERAP1
SCHEMBL29881377 0.89 CTSD (0.35) BACE1MMECTSD
SCHEMBL7163139 0.88 BACE1 (0.42) BACE1ERAP2CTSDCTSBIL1RN
SCHEMBL7163147 0.88 BACE1 (0.42) BACE1ERAP2CTSDCTSBIL1RN
SCHEMBL29532207 0.88 MME (0.41) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105683390-B HbA1c measurement method using amadoriase acting on glycosylated peptide 龟甲万株式会社 2021-02-26 CN claimed
CN-105683390-B HbA1c measurement method using amadoriase acting on glycosylated peptide 龟甲万株式会社 2021-02-26 CN disclosed
US-8268017-B2 Method for stabilizing leuco-type colorant ASAHI KASEI PHARMA CORPORATION (JP) 2012-09-18 US disclosed
US-20080295259-A1 METHOD FOR STABILIZING LEUCO-TYPE COLORANT ASAHI KASEI PHARMA CORPORATION (JP) 2008-12-04 US disclosed
US-20070224685-A1 Reagent Containing Protease Reaction Promoter and/or Colorant Stabilizer ASAHI KASEI PHARMA CORPORATION (JP) 2007-09-27 US disclosed
EP-1788081-A1 REAGENT CONTAINING PROTEASE REACTION PROMOTER AND/OR COLORANT STABILIZER Asahi Kasei Pharma Corporation (JP) 2007-05-23 EP disclosed