Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15082166 | 0.82 | ESR1 (0.59) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL93780 | 0.80 | ESR1 (0.57) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL679829 | 0.80 | ESR1 (0.57) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL9412151 | 0.80 | ESR1 (0.57) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL28477538 | 0.80 | ESR1 (0.57) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL4916342 | 0.78 | ESR1 (0.55) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL12152079 | 0.78 | ESR1 (0.55) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL11464625 | 0.78 | ESR1 (0.55) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL3653417 | 0.78 | ESR1 (0.55) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL7492813 | 0.77 | RIPK1 (0.57) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312339-A1 | FLUORINE-SUBSTITUTED ALKYL PHENOL COMPOUNDS AND THEIR USES | BAKER MAX T | 2008-12-18 | — | — | US | disclosed |
| US-7312250-B2 | Fluorine-substituted alkyl phenol compounds and their uses | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-20030176513-A1 | Fluorine-substituted alkyl phenol compounds and their uses | IOWA RESEARCH FOUNDATION, UNIVERSITY OF | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176513-A1 | Fluorine-substituted alkyl phenol compounds and their uses | AFF4, AFF1, AFF2 | ESR1 328/4885ESR2 1859/4885PDCD1 4149/4885 |
| US-20080312339-A1 | FLUORINE-SUBSTITUTED ALKYL PHENOL COMPOUNDS AND THEIR USES | AFF4, AFF1, AFF2 | ESR1 328/4885ESR2 1859/4885PDCD1 4149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.