Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4562781 | 1.00 | HDAC1 (0.54) | HDAC1HDAC6CXCR4ADORA2ACYP2D6 | |
| SCHEMBL4885407 | 0.85 | HDAC1 (0.56) | HDAC1HDAC6CXCR4ADORA2ACYP2D6 | |
| SCHEMBL4885421 | 0.85 | HDAC1 (0.56) | HDAC1HDAC6CXCR4ADORA2ACYP2D6 | |
| SCHEMBL4113740 | 0.84 | HDAC1 (0.48) | HDAC1HDAC6CXCR4ADORA2ACYP2D6 | |
| SCHEMBL4882672 | 0.84 | HDAC1 (0.48) | HDAC1HDAC6CXCR4ADORA2ACYP2D6 | |
| SCHEMBL3736077 | 0.83 | HDAC1 (0.54) | HDAC1HDAC6CXCR4ADORA2ACYP2D6 | |
| SCHEMBL4889228 | 0.83 | HDAC1 (0.54) | HDAC1HDAC6CXCR4ADORA2ACYP2D6 | |
| SCHEMBL4123198 | 0.83 | HDAC1 (0.54) | HDAC1HDAC6CXCR4ADORA2ACYP2D6 | |
| SCHEMBL13909820 | 0.81 | HDAC1 (0.76) | HDAC1HDAC6CXCR4CYP2D6CYP3A4 | |
| SCHEMBL30379489 | 0.81 | HDAC1 (0.61) | HDAC1HDAC6CXCR4ADORA2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096861-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096861-A1 | Chemical Compounds | CCR5, CXCR4, CXCR3 | HDAC1 844/4885HDAC6 568/4885CXCR4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.