Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616297 | 0.86 | KMT2A (0.76) | MEN1KMT2AALDH1A1ALPLLMNA | |
| SCHEMBL14924456 | 0.86 | MEN1 (1.00) | MEN1KMT2AALDH1A1CHRM2HTT | |
| SCHEMBL12947818 | 0.84 | KMT2A (0.69) | MEN1KMT2AALDH1A1HRH3HTT | |
| SCHEMBL2616165 | 0.84 | MEN1 (0.69) | MEN1KMT2AALDH1A1USP2LMNA | |
| Hydrochloric Acid SCHEMBL1495931 | 0.83 | MEN1 (0.67) | MEN1KMT2AALDH1A1USP2ALPL | |
| SCHEMBL28484919 | 0.83 | ALDH1A1 (0.73) | MEN1KMT2AALDH1A1USP2HRH3 | |
| SCHEMBL1140551 | 0.82 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1USP2HRH3 | |
| SCHEMBL13316842 | 0.82 | MEN1 (0.69) | MEN1KMT2AALDH1A1HRH3CHRM2 | |
| SCHEMBL9871356 | 0.81 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1USP2ALPL | |
| SCHEMBL1002669 | 0.81 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1ALPLALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234498-A1 | Pyrovalerone Analogues and Therapeutic Uses Thereof | PRESIDENT AND FELLOW OF HARVARD COLLEGE (US) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234498-A1 | Pyrovalerone Analogues and Therapeutic Uses Thereof | SLC6A2, SLC6A4, SLC6A3 | MEN1 1560/4885KMT2A 3331/4885ALDH1A1 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.