Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357823 | 0.98 | KMT2A (0.53) | KMT2AHPGDCA1CA2PRSS1 | |
| SCHEMBL28041171 | 0.85 | KMT2A (0.52) | KMT2AHPGDCA1CA2PRSS1 | |
| SCHEMBL9040129 | 0.85 | KMT2A (0.52) | KMT2AHPGDCA1CA2PRSS1 | |
| SCHEMBL6916227 | 0.83 | KMT2A (0.50) | KMT2AHPGDCA1CA2PRSS1 | |
| SCHEMBL10950994 | 0.83 | KMT2A (0.50) | KMT2AHPGDCA1CA2PRSS1 | |
| SCHEMBL7068759 | 0.83 | HPGD (0.48) | KMT2AHPGDCA1CA2PRSS1 | |
| SCHEMBL10434708 | 0.82 | KMT2A (0.49) | KMT2AHPGDCA1CA2PRSS1 | |
| SCHEMBL7630233 | 0.82 | KMT2A (0.49) | KMT2AHPGDCA1CA2PRSS1 | |
| SCHEMBL28588753 | 0.81 | TXNRD1 (0.39) | KMT2AHPGDCA1CA2CA9 | |
| SCHEMBL6913132 | 0.80 | KMT2A (0.47) | KMT2AHPGDCA1CA2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110252-B1 | HEAT-SENSITIVE REGISTRATION MATERIAL | BASF Aktiengesellschaft (DE) | 1985-11-13 | — | — | EP | claimed |
| US-4523208-A | SULFONIC ACID ESTER AS ACTIVATOR | BASF AKTIENGESELLSCHAFT (DE) | 1985-06-11 | — | — | US | claimed |
| US-4383126-A | Preparation of monoalkyl ethers of hydroxyphenols | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-10 | — | — | US | claimed |
| CN-118688346-A | Application of polymer modified silica gel adsorption material in analysis of sulfonate genotoxic impurities | 山东大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-109071960-B | Silicon-containing heterocyclic matting agents, compounds and polymers | 富士胶片和光纯药株式会社 | 2021-01-12 | — | — | CN | disclosed |
| CN-111218126-A | Matting agent, compound and polymer | 富士胶片和光纯药株式会社 | 2020-06-02 | — | — | CN | disclosed |
| CN-107001807-B | Compound and polymer | 富士胶片和光纯药株式会社 | 2020-04-03 | — | — | CN | disclosed |
| CN-108840793-A | A kind of method that application simulation mobile bed chromatic prepares gamma-thujaplicin | 辽宁科技大学 | 2018-11-20 | — | — | CN | disclosed |
| EP-2474536-B1 | PROCESS FOR PREPARATION OF PYRIMIDINYLACETONITRILE DERIVATIVES AND INTERMEDIATES FOR SYNTHESIS THEREOF | IHARA CHEMICAL IND CO (JP) | 2014-06-25 | — | — | EP | disclosed |
| CN-102093257-B | Method for preparing 2,2-diisopropylpropionitrile | WENZHOU ZHONGTAI CHEMICAL CO LTD | 2013-09-11 | — | — | CN | disclosed |
| US-20120178931-A1 | PROCESS FOR PREPARATION OF PYRIMIDINYLACETONITRILE DERIVATIVES AND INTERMEDIATES FOR SYNTHESIS THEREOF | IHARA CHEMICAL INDUSTRY CO., LTD (JP) | 2012-07-12 | — | — | US | disclosed |
| EP-0387360-B1 | CYANINE COMPOUNDS | ASAHI CHEMICAL CO (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5087704-A | Infrared light absorbing dye for use in optical recording media or semiconductor laser recording | ASAHI CHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| US-5055589-A | Chemical intermediate for cyanine dyes | ASAHI CHEMICAL CO., LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| US-5023366-A | Reacted with a benzyl halide, alcohol or ether; for pressure sensitive elements | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-06-11 | — | — | US | disclosed |
| US-5008401-A | Cyanine compounds | ASAHI CHEMICAL CO., LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0387357-A1 | INDOLENINE DERIVATIVES | ASAHI CHEMICAL CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |
| EP-0387360-A1 | CYANINE COMPOUNDS | ASAHI CHEMICAL CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |
| US-4406905-A | COMPLEXING, ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1983-09-27 | — | — | US | disclosed |
| US-4383126-A | Preparation of monoalkyl ethers of hydroxyphenols | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178931-A1 | PROCESS FOR PREPARATION OF PYRIMIDINYLACETONITRILE DERIVATIVES AND INTERMEDIATES FOR SYNTHESIS THEREOF | DPYD, UMPS, PNP | KMT2A 1075/4885HPGD 405/4885CA1 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.