Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK14 | O94921 | 15/20 | 0.46 |
| ▸ | CCNY | Q8ND76 | 13/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
| ▸ | CASK | O14936 | 1/20 | 0.43 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | MAK | P20794 | 1/20 | 0.43 |
| ▸ | CDK11B | P21127 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14114409 | 0.88 | CDK5 (0.47) | CDK14CCNYCCNT1CDK9CDK5 | |
| SCHEMBL2029686 | 0.83 | CDK14 (0.48) | CDK14CCNYLMNARAB9ACNR1 | |
| SCHEMBL23271141 | 0.81 | CDK14 (0.71) | CDK14CCNY | |
| SCHEMBL17252164 | 0.79 | CDK14 (0.70) | CDK14CCNYCCNT1CDK9CDK5 | |
| SCHEMBL23270992 | 0.78 | CDK14 (0.75) | CDK14CCNYCDK2CDK16 | |
| SCHEMBL23270991 | 0.78 | CDK14 (0.75) | CDK14CCNYCDK2CDK16 | |
| SCHEMBL13993660 | 0.78 | LMNA (0.46) | CDK14CCNYLMNARAB9ACNR1 | |
| SCHEMBL8262596 | 0.77 | CDK14 (0.43) | CDK14CCNYLMNARAB9ACNR1 | |
| SCHEMBL8261492 | 0.77 | CDK2 (0.49) | CDK14CCNYLMNARAB9ACNR1 | |
| SCHEMBL8263999 | 0.77 | CDK14 (0.52) | CDK14CCNYLMNARAB9ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167309-A1 | Pharmaceutical Compounds | ASTEX THERAPEUTICS, LTD. (UK) | 2008-07-10 | — | — | US | disclosed |
| US-20080167309-A1 | Pharmaceutical Compounds | ASTEX THERAPEUTICS, LTD. (UK) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167309-A1 | Pharmaceutical Compounds | CCNO, CDK2, CDK1 | CDK14 38/4885CCNY 10/4885LMNA 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.