Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Beta-Pinene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beta-Pinene SCHEMBL5086803 | 0.95 | TRPA1 (0.33) | TRPA1PTPN2PTPN1MAPK1TSHR | |
| Beta-Pinene SCHEMBL900792 | 0.89 | TSHR (0.38) | TRPA1MAPK1TSHR | |
| Beta-Pinene SCHEMBL1532504 | 0.89 | TSHR (0.38) | TRPA1MAPK1TSHR | |
| (+)-Beta-Pinene SCHEMBL3506800 | 0.89 | TSHR (0.38) | TRPA1MAPK1TSHR | |
| Beta-Pinene SCHEMBL13300 | 0.89 | TSHR (0.38) | TRPA1MAPK1TSHR | |
| Beta-Pinene SCHEMBL12971319 | 0.87 | TSHR (0.36) | TRPA1MAPK1TSHR | |
| Beta-Pinene SCHEMBL12986238 | 0.87 | TSHR (0.36) | TRPA1MAPK1TSHR | |
| Beta-Pinene SCHEMBL6989826 | 0.87 | TSHR (0.36) | TRPA1MAPK1TSHR | |
| Beta-Pinene SCHEMBL8027407 | 0.81 | BLM (0.34) | PTPN1 | |
| Picloram SCHEMBL2874020 | 0.74 | TDP1 (0.52) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043867-A1 | ASPHALT ADDITIVE, AND ASPHALT COMPOSITION AND PREPARATION METHOD THEREFOR | 中国石油化工股份有限公司 | 2025-03-06 | — | — | WO | disclosed |
| US-7399645-B2 | Constrained cis-diol-borate bioconjugation system | APPLERA CORPORATION (US) | 2008-07-15 | — | — | US | disclosed |
| US-20070287825-A1 | Constrained cis-diol-borate bioconjugation system | APPLERA CORPORATION | 2007-12-13 | — | — | US | disclosed |
| US-20050277143-A1 | Constrained cis-diol-borate bioconjugation system | APPLERA CORPORATION (US) | 2005-12-15 | — | — | US | disclosed |
| WO-2005119255-A2 | CONSTRAINED CIS-DIOL-BORATE BIOCONJUGATION SYSTEM | APPLERA CORPORATION (US) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287825-A1 | Constrained cis-diol-borate bioconjugation system | TAC3, CCR3, B3GAT3 | TRPA1 4125/4885PTPN2 4548/4885PTPN1 4649/4885 |
| US-20050277143-A1 | Constrained cis-diol-borate bioconjugation system | TAC3, CCR3, B3GAT3 | TRPA1 4125/4885PTPN2 4548/4885PTPN1 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.