Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73490 | 0.82 | GSK3B (1.00) | GSK3BALDH1A1CES1TDP1CA1 | |
| Hydrochlorthiazide SCHEMBL4936607 | 0.80 | GSK3B (0.61) | GSK3BMAPTALDH1A1MEN1KMT2A | |
| Methylsulfanylmethane SCHEMBL28782214 | 0.78 | GSK3B (0.89) | GSK3BMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7369237 | 0.78 | GSK3B (0.89) | GSK3BALDH1A1CES1TDP1CA1 | |
| Paranitrobenzyl Alcohol SCHEMBL28146144 | 0.77 | POLB (0.49) | MAPTALDH1A1KMT2ACYP19A1L3MBTL1 | |
| Hydrochlorthiazide SCHEMBL27468616 | 0.75 | CYP1A2 (0.46) | GSK3BMAPTALDH1A1MEN1KMT2A | |
| 4-Nitroaniline SCHEMBL27694794 | 0.75 | ALDH1A1 (0.60) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| Nitrobenzene SCHEMBL27321664 | 0.75 | ALDH1A1 (0.57) | MAPTALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL40529 | 0.74 | GSK3B (0.81) | GSK3BMAPTMEN1KMT2AKDM4E | |
| Acetonitrile SCHEMBL27927677 | 0.74 | GSK3B (0.81) | GSK3BMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293931-A1 | Methods and compositions for the removal of nucleic acid amplification inhibitors | LOS ALAMOS NATIONAL SECURITY, LLC | 2008-11-27 | — | — | US | disclosed |
| US-20070065841-A1 | Methods and compositions for the removal of nucleic acid amplification inhibitors | ENERGY, U.S. DEPARTMENT OF | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293931-A1 | Methods and compositions for the removal of nucleic acid amplification inhibitors | POLRMT, FBL, POLL | GSK3B 3452/4885MAPT 2739/4885ALDH1A1 2004/4885 |
| US-20070065841-A1 | Methods and compositions for the removal of nucleic acid amplification inhibitors | POLRMT, FBL, POLL | GSK3B 3452/4885MAPT 2739/4885ALDH1A1 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.