Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.56 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | COMT | P21964 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4937320 | 1.00 | MEN1 (0.56) | MEN1KMT2AFTOABCC3ABCC4 | |
| SCHEMBL14345708 | 0.91 | MEN1 (0.46) | MEN1KMT2AFTOABCC3ABCC4 | |
| SCHEMBL4935282 | 0.90 | KMT2A (0.57) | MEN1KMT2AFTOABCC3ABCC4 | |
| SCHEMBL4935276 | 0.90 | KMT2A (0.57) | MEN1KMT2AFTOABCC3ABCC4 | |
| SCHEMBL4939490 | 0.90 | FTO (0.61) | MEN1KMT2AFTOABCC3ABCC4 | |
| SCHEMBL4939448 | 0.90 | MEN1 (0.56) | MEN1KMT2AFTOABCC3ABCC4 | |
| SCHEMBL4939455 | 0.90 | MEN1 (0.56) | MEN1KMT2AFTOABCC3ABCC4 | |
| SCHEMBL5329066 | 0.89 | FTO (0.62) | MEN1KMT2AFTOABCC3ABCC4 | |
| SCHEMBL5329070 | 0.89 | FTO (0.62) | MEN1KMT2AFTOABCC3ABCC4 | |
| SCHEMBL5325512 | 0.89 | KMT2A (0.54) | MEN1KMT2AFTOABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103191-A1 | ENTACAPONE-DERIVATIVES | SCHWARZ PHARMA AG (DE) | 2008-05-01 | — | — | US | claimed |
| WO-2007144169-A2 | ENTACAPONE-DERIVATIVES | SCHWARZ PHARMA AG (DE) | 2007-12-21 | — | — | WO | claimed |
| US-20080103191-A1 | ENTACAPONE-DERIVATIVES | SCHWARZ PHARMA AG (DE) | 2008-05-01 | — | — | US | disclosed |
| WO-2007144169-A2 | ENTACAPONE-DERIVATIVES | SCHWARZ PHARMA AG (DE) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103191-A1 | ENTACAPONE-DERIVATIVES | ENTPD5, ENTPD3, ENTPD1 | MEN1 1023/4885KMT2A 4545/4885FTO 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.