SCHEMBL4937641

SCHEMBL4937641

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
THRB P10828 1/20 0.38
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28701223 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL6278209 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL28699116 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL7626574 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL1169605 1.00 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL28420410 0.96 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL396407 0.96 LMNA (0.41) LMNATHRBCA2
Perflisopent SCHEMBL1509322 0.92 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL760447 0.91 LMNA (0.35) LMNA
SCHEMBL62446 0.91 LMNA (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765060-B2 Chemical sensor REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2014-07-01 US claimed
US-20080293997-A1 Chemical Sensor NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-11-27 US claimed
EP-1888330-A2 CHEMICAL SENSOR The Regents of the University of Minnesota (US) 2008-02-20 EP claimed
WO-2006127963-A2 CHEMICAL SENSOR REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2006-11-30 WO claimed
EP-3629928-B1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE THE UNIV OF TENNESSEE RESEARCH FOUNDATION (US) 2025-11-05 EP disclosed
US-11686722-B2 Compositions and methods to detect molecules in a sample INFUSENSE CORP. (US) 2023-06-27 US disclosed
US-11375929-B2 Method and device for detection of bioavailable drug concentration in a fluid sample THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2022-07-05 US disclosed
EP-3629928-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE The University of Tennessee Research Foundation (US) 2020-04-08 EP disclosed
US-20190331656-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE INFUSENSE CORP. 2019-10-31 US disclosed
EP-3555609-A1 COMPOSITIONS AND METHODS TO DETECT MOLECULES IN A SAMPLE Infusense Corp. (US) 2019-10-23 EP disclosed
WO-2018222820-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2018-12-06 WO disclosed
US-20180271413-A1 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE UNITED STATES GOVERNMENT 2018-09-27 US disclosed
EP-0472422-B1 Oligohexafluoropropylene compounds and methods of making them SHINETSU CHEMICAL CO (JP) 1995-01-11 EP disclosed
US-5288376-A Preparation of perfluorooligoether iodides SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-02-22 US disclosed
US-5278340-A Perfluoroalkyl group SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-01-11 US disclosed
EP-0520821-A1 Oligohexafluoropropylene oxide derivative and process of producing the same Shin-Etsu Chemical Co., Ltd. (JP) 1992-12-30 EP disclosed
US-5130477-A Iodination of carbonyl fluorides with metal iodides SHIN-ETSU CHEMICAL COMPANY LIMITED (JP) 1992-07-14 US disclosed
EP-0472422-A2 Oligohexafluoropropylene compounds and methods of making them SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-02-26 EP disclosed
EP-0472423-A2 Preparation of perfluorooligoether iodides SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-02-26 EP disclosed
US-4769184-A DECOMPOSITION OF A PERFLUOROPOLYETHER NIPPON MEKTRON LIMITED (JP) 1988-09-06 US disclosed