Perflisopent

Perflisopent

SCHEMBL1509322

FC(F)(F)C(F)(F)C(F)(C(F)(F)F)C(F)(F)F.FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
THRB P10828 1/20 0.38
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6278209 0.92 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL28701223 0.92 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL7626574 0.92 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL1169605 0.92 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL4937641 0.92 LMNA (0.47) LMNATHRBCA2CA1MMP1
SCHEMBL28699116 0.92 LMNA (0.47) LMNATHRBCA2CA1MMP1
Perflisopent SCHEMBL814397 0.91 LMNA (0.35) LMNA
SCHEMBL62357 0.88 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL28420410 0.88 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL396407 0.87 LMNA (0.41) LMNATHRBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748501-B2 Polyurethane foam composition and polyurethane foam prepared using same SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-06-10 US disclosed
US-20110054052-A1 POLYURETHANE FOAM COMPOSITION AND POLYURETHANE FOAM PREPARED USING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-03-03 US disclosed