SCHEMBL493774

SCHEMBL493774

CCCCC#Cc1cccc(C=O)c1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.45
MAPT P10636 2/20 0.42
MAPK1 P28482 1/20 0.40
KCNH2 Q12809 1/20 0.40
ALDH1A1 P00352 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
CYP2D6 P10635 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
MMP2 P08253 1/20 0.36
MMP12 P39900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9700186 0.95 KCNH2 (0.45) FFAR1MAPTMAPK1KCNH2ALDH1A1
SCHEMBL7680519 0.94 KCNH2 (0.48) FFAR1MAPTMAPK1KCNH2ALDH1A1
SCHEMBL8846088 0.94 KCNH2 (0.48) FFAR1MAPTMAPK1KCNH2ALDH1A1
SCHEMBL1852576 0.94 KCNH2 (0.48) FFAR1MAPTMAPK1KCNH2ALDH1A1
SCHEMBL10795164 0.94 KCNH2 (0.48) FFAR1MAPTMAPK1KCNH2ALDH1A1
SCHEMBL9559955 0.86 FFAR1 (0.52) FFAR1MAPTALDH1A1FFAR4HRH3
SCHEMBL30688451 0.81 FFAR1 (0.50) FFAR1ALDH1A1
SCHEMBL3899508 0.81 FFAR1 (0.50) FFAR1ALDH1A1
SCHEMBL6087379 0.80 FFAR1 (0.47) FFAR1MAPTKCNH2ALDH1A1FFAR4
SCHEMBL9442275 0.80 MAOA (0.48) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2199290-B1 Method of nucleating a polyolefin composition with acetal-based compounds MILLIKEN & CO (US) 2018-06-06 EP claimed
EP-2663542-B1 PROCESS FOR THE PREPARATION OF ALDITOL ACETALS RELIANCE IND LTD (IN) 2016-07-06 EP claimed
US-9029575-B2 Process for preparation of acetals RELIANCE INDUSTRIES LIMITED (IN) 2015-05-12 US claimed
US-8969595-B2 Method of making diacetal compound in aqueous medium RELIANCE INDUSTRIES LIMITED (IN) 2015-03-03 US claimed
US-8871954-B2 Process for the preparation of alditol acetals RELIANCE INDUSTRIES LIMITED (IN) 2014-10-28 US claimed
EP-2663541-A1 METHOD OF MAKING DIACETAL COMPOUND IN AQUEOUS MEDIUM Reliance Industries Limited (IN) 2013-11-20 EP claimed
EP-2663542-A1 PROCESS FOR THE PREPARATION OF ALDITOL ACETALS Reliance Industries Limited (IN) 2013-11-20 EP claimed
EP-2663569-A1 PROCESS FOR PREPARING ALDITOL ACETALS Reliance Industries Limited (IN) 2013-11-20 EP claimed
US-20130303787-A1 Process For Preparing Alditol Acetals RELIANCE INDUSTRIES LIMITED (IN) 2013-11-14 US claimed
US-20130296581-A1 Process For The Preparation of Alditol Acetals RELIANCE INDUSTRIES LIMITED (IN) 2013-11-07 US claimed
EP-1740653-B1 METHOD OF NUCLEATING A POLYOLEFIN COMPOSITION WITH ACETAL-BASED COMPOUNDS MILLIKEN & CO (US) 2010-08-18 EP claimed
EP-2199290-A2 Method of nucleating a polyolefin composition with acetal-based compounds Milliken & Company (US) 2010-06-23 EP claimed
US-7262236-B2 Acetal-based compositions MILLIKEN & COMPANY (US) 2007-08-28 US claimed
EP-1740653-A4 METHOD OF NUCLEATING A POLYOLEFIN COMPOSITION WITH ACETAL-BASED COMPOUNDS MILLIKEN & CO (US) 2007-07-04 EP claimed
EP-1740653-A2 METHOD OF NUCLEATING A POLYOLEFIN COMPOSITION WITH ACETAL-BASED COMPOUNDS Milliken & Company (US) 2007-01-10 EP claimed
US-7157510-B2 Method of nucleating a polyolefin composition with acetal-based compounds MILLIKEN & COMPANY (US) 2007-01-02 US claimed
WO-2005111134-A2 METHOD OF NUCLEATING A POLYOLEFIN COMPOSITION WITH ACETAL-BASED COMPOUNDS MILLIKEN & COMPANY (US) 2005-11-24 WO claimed
WO-2005108479-A2 ACETAL-BASED COMPOSITIONS MILLIKEN & COMPANY (US) 2005-11-17 WO claimed
US-20050239928-A1 Acetal-based compositions MILLIKEN & COMPANY 2005-10-27 US claimed
US-20050239926-A1 Method of nucleating a polyolefin composition with acetal-based compounds MILLIKEN & COMPANY 2005-10-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239928-A1 Acetal-based compositions PCNA, RAD51, AR FFAR1 1743/4885MAPT 2567/4885MAPK1 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.