Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071009 | 0.93 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL166756 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL17785958 | 0.85 | GAA (0.44) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL1071007 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL27375665 | 0.81 | GAA (0.46) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL11709719 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10KDM4ETSHR | |
| SCHEMBL166758 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL28415363 | 0.79 | NAAA (0.36) | ALDH1A1LMNAHSD17B10SOAT1TSHR | |
| Triethyl Citrate SCHEMBL23465 | 0.77 | GAA (0.48) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Triethyl Citrate SCHEMBL901127 | 0.77 | GAA (0.48) | ALDH1A1LMNAHSD17B10GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8603528-B2 | Compositions and method for the reduction of post-operative pain | ABYRX, INC. (US) | 2013-12-10 | — | — | US | disclosed |
| US-20130109651-A1 | Absorbable Implants And Methods Of Their Use In Hemostasis And In The Treatment Of Osseous Defects | ORTHOCON, INC. (US) | 2013-05-02 | — | — | US | disclosed |
| US-8337879-B2 | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects | ORTHOCON, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8309131-B2 | Absorbable putty-like implants and methods for their use for mechanical hemostasis of bone and for the treatment of osseous defects | ORTHOCON, INC. (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120189671-A1 | Absorbable Implants and Methods for their use in Hemostasis | ORTHOCON, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| EP-2462958-A2 | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects | Orthocon Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2462957-A2 | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects | Orthocon Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20120027817-A1 | Absorbable Implants and Methods for Their Use in Hemostasis | ORTHOCON, INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-8105628-B2 | Mixture of biocompatible putty containing bulking agent, metal compound and polymer | ORTHOCON, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20110280970-A1 | ABSORBABLE PUTTY-LIKE IMPLANTS AND METHODS FOR THEIR USE FOR MECHANICAL HEMOSTASIS OF BONE AND FOR THE TREATMENT OF OSSEOUS DEFECTS | ORTHOCON, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| EP-1912630-A2 | COMPOSITIONS AND METHODS FOR THE REDUCTION OF POST-OPERATIVE PAIN | Orthocon, Inc. (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007014210-A2 | COMPOSITIONS AND METHODS FOR THE REDUCTION OF POST-OPERATIVE PAIN | ORTHOCON, INC. (US) | 2007-02-01 | — | — | WO | disclosed |
| US-20060280801-A1 | Compositions and method for the reduction of post-operative pain | ABYRX, INC. | 2006-12-14 | — | — | US | disclosed |
| EP-1677708-A1 | BIOABSORBABLE PUTTY-LIKE HEMOSTATIC IMPLANTS | Orthocon, LLC (US) | 2006-07-12 | — | — | EP | disclosed |
| EP-1677664-A2 | ABSORBABLE IMPLANTS AND METHODS FOR THEIR USE IN HEMOSTASIS AND IN THE TREATMENT OF OSSEOUS DEFECTS | Ortho Therapeutics, LLC. (US) | 2006-07-12 | — | — | EP | disclosed |
| US-20060013857-A1 | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects | ABYRX, INC. | 2006-01-19 | — | — | US | disclosed |
| US-20060002976-A1 | Absorbable putty-like implants and methods for their use for mechanical hemostasis of bone and for the treatment of osseous defects | ABYRX, INC. | 2006-01-05 | — | — | US | disclosed |
| WO-2005034816-A1 | BIOABSORBABLE PUTTY-LIKE HEMOSTATIC IMPLANTS | ORTHO THERAPEUTICS, LLC. (US) | 2005-04-21 | — | — | WO | disclosed |
| WO-2005034726-A2 | ABSORBABLE IMPLANTS AND METHODS FOR THEIR USE IN HEMOSTASIS AND IN THE TREATMENT OF OSSEOUS DEFECTS | ORTHO THERAPEUTICS, LLC (US) | 2005-04-21 | — | — | WO | disclosed |
| US-20050065214-A1 | Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects | ABYRX, INC. | 2005-03-24 | — | — | US | disclosed |