SCHEMBL4938816

SCHEMBL4938816

CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC[C@@H](CO)C[C@@H]21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 9/20 1.00
▸ CNR1 P21554 6/20 1.00
▸ NR1I2 O75469 1/20 0.68
▸ ADORA3 P0DMS8 1/20 0.68
▸ SLC6A3 Q01959 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31545255 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL31545949 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL31544860 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL31545317 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL23602215 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL31545768 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL23602072 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL17414492 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL13990796 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL31546023 0.93 CNR2 (0.86) CNR2CNR1NR1I2ADORA3SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060160776-A1 Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage PHARMACIA CORPORATION 2006-07-20 — — US claimed
WO-2004105699-A2 COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A CANNABINOID AGENT FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE PHARMACIA CORPORATION (US) 2004-12-09 — — WO claimed
US-12338289-B2 Antibody variant combinations and uses thereof GENMAB B.V. (NL) 2025-06-24 — — US disclosed
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 — — US disclosed
US-20210198223-A1 METHODS AND COMPOSITIONS RELATING TO ULTRAPURE 5-(1,1-DIMETHYLHEPTYL)-RESORCINOL CORBUS PHARMACEUTICALS, INC. 2021-07-01 — — US disclosed
US-10894069-B2 Topical antiviral formulations and methods of using the same MCELVANY CHRISTOPHER A (US) 2021-01-19 — — US disclosed
US-20200230187-A1 TOPICAL ANTIVIRAL FORMULATIONS AND METHODS OF USING THE SAME MCELVANY CHRISTOPHER A (US) 2020-07-23 — — US disclosed
US-10456435-B2 Topical antiviral formulations and methods of using the same MCELVANY, Christopher A. (US) 2019-10-29 — — US disclosed
US-20180207213-A1 TOPICAL ANTIVIRAL FORMULATIONS AND METHODS OF USING THE SAME MCELVANY, CHRISTOPHER 2018-07-26 — — US disclosed
US-8486374-B2 Alcohol-free drug or cosmetics carrier mixture of water, hydrophobic solvent, surfactant and gelling agent; oil in water emulsions FOAMIX LTD. (IL) 2013-07-16 — — US disclosed
US-20080292560-A1 SILICONE IN GLYCOL PHARMACEUTICAL AND COSMETIC COMPOSITIONS WITH ACCOMMODATING AGENT FOAMIX PHARMACEUTICALS LTD. (IL) 2008-11-27 — — US disclosed
US-20080063607-A1 Oleaginous pharmaceutical and cosmetic foam FOAMIX LTD 2008-03-13 — — US disclosed
US-20070292461-A1 Oleaginous pharmaceutical and cosmetic foam FOAMIX LTD. (IL) 2007-12-20 — — US disclosed
US-20060160776-A1 Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage PHARMACIA CORPORATION 2006-07-20 — — US disclosed
WO-2004105699-A2 COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A CANNABINOID AGENT FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE PHARMACIA CORPORATION (US) 2004-12-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080292560-A1 SILICONE IN GLYCOL PHARMACEUTICAL AND COSMETIC COMPOSITIONS WITH ACCOMMODATING AGENT SSTR2, SSTR3, LPXN CNR2 1130/4885CNR1 1270/4885NR1I2 1640/4885
US-20210198223-A1 METHODS AND COMPOSITIONS RELATING TO ULTRAPURE 5-(1,1-DIMETHYLHEPTYL)-RESORCINOL CNR1, DHCR24, CNR2 CNR2 3/4885CNR1 1/4885NR1I2 460/4885
US-20070292461-A1 Oleaginous pharmaceutical and cosmetic foam LIPA, LIPC, PLIN3 CNR2 413/4885CNR1 382/4885NR1I2 986/4885
US-20080063607-A1 Oleaginous pharmaceutical and cosmetic foam LIPA, LIPC, PLIN3 CNR2 413/4885CNR1 382/4885NR1I2 986/4885
US-20060160776-A1 Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage CNR2, CNR1, PTGS2 CNR2 1/4885CNR1 2/4885NR1I2 656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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