SCHEMBL4938839

SCHEMBL4938839

O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)[C@@H](COCc1ccccc1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.42
SLC1A1 P43005 1/20 0.42
FOLH1 Q04609 1/20 0.41
CA1 P00915 8/20 0.40
CA2 P00918 6/20 0.40
CA4 P22748 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRA2A P08913 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
DRD1 P21728 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
CYP2C19 P33261 1/20 0.39
ADRA1A P35348 1/20 0.39
DRD3 P35462 1/20 0.39
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406971 1.00 MAOB (0.42) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL1144138 1.00 MAOB (0.42) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL8059292 0.99 MAOB (0.43) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL8068462 0.99 MAOB (0.43) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL8068485 0.99 MAOB (0.43) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL8059372 0.95 SLC1A1 (0.44) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL6443574 0.94 FOLH1 (0.46) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL7594884 0.93 SLC1A1 (0.47) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL29742385 0.93 MAOB (0.42) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL6443585 0.91 MAOB (0.38) MAOBSLC1A1FOLH1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080003632-A1 Method for the In Vitro Determination of Cellular Uptake of Exogenous and Endogenous Substances Using Nmr Shift Agents and the Magic Angle Nmr Technique BRACCO IMAGING SPA (IT) 2008-01-03 US claimed