SCHEMBL1144138

SCHEMBL1144138

O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)C(COCc1ccccc1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.42
SLC1A1 P43005 1/20 0.42
FOLH1 Q04609 1/20 0.41
CA1 P00915 8/20 0.40
CA2 P00918 6/20 0.40
CA4 P22748 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRA2A P08913 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
DRD1 P21728 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
CYP2C19 P33261 1/20 0.39
ADRA1A P35348 1/20 0.39
DRD3 P35462 1/20 0.39
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406971 1.00 MAOB (0.42) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL4938839 1.00 MAOB (0.42) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL8059292 0.99 MAOB (0.43) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL8068462 0.99 MAOB (0.43) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL8068485 0.99 MAOB (0.43) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL8059372 0.95 SLC1A1 (0.44) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL6443574 0.94 FOLH1 (0.46) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL7594884 0.93 SLC1A1 (0.47) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL29742385 0.93 MAOB (0.42) MAOBSLC1A1FOLH1CA1CA2
SCHEMBL6443585 0.91 MAOB (0.38) MAOBSLC1A1FOLH1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3325992-B1 QUANTITATIVE MAGNETIC RESONANCE IMAGING OF THE VASCULATURE UNIV NORTHEASTERN (US) 2026-01-28 EP claimed
US-20250064988-A1 MRI-AGENT LOADED PLATELET COMPOSITIONS AND METHODS OF PREPARING AND USING THE SAME CELLPHIRE, INC. (US) 2025-02-27 US claimed
WO-2023245169-A1 ANTIMICROBIAL PEPTIDE COMBINATIONS Vestaron Corporation (US) 2023-12-21 WO claimed
WO-2023220694-A1 MRI-AGENT LOADED PLATELET COMPOSITIONS AND METHODS OF PREPARING AND USING THE SAME CELLPHIRE, INC. (US) 2023-11-16 WO claimed
CN-116440315-A Multi-mode developed gelatin sponge microsphere and preparation method thereof 海南百迈科医疗科技股份有限公司 2023-07-18 CN claimed
CN-113209304-B Chelated calcium self-assembled nano particle and preparation method and application thereof 复旦大学附属金山医院(上海市金山区核化伤害应急救治中心、上海市金山区眼病防治所) 2023-01-24 CN claimed
US-11383008-B2 Surface-modified polymeric substrates grafted with a properties-imparting compound using clip chemistry CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-07-12 US claimed
US-11110185-B2 Combination formulation GE HEALTHCARE AS (NO) 2021-09-07 US claimed
EP-3474911-B1 SURFACE-MODIFIED POLYMERIC SUBSTRATES GRAFTED WITH A PROPERTIES-IMPARTING COMPOUND USING CLIP CHEMISTRY CENTRE NAT RECH SCIENT (FR) 2020-12-30 EP claimed
US-20190247551-A1 SURFACE-MODIFIED POLYMERIC SUBSTRATES GRAFTED WITH A PROPERTIES-IMPARTING COMPOUND USING CLIP CHEMISTRY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2019-08-15 US claimed
EP-1423436-B1 USE OF HEPARINOID DERIVATIVES FOR TREATING AND DIAGNOSING DISEASES THAT CAN BE TREATED BY HEPARINOIDS SANOFI AVENTIS DEUTSCHLAND (DE) 2006-04-12 EP claimed
US-20050175543-A1 Distinguish between tumor cells and normal cells using novel contrast agents that contain a Magnetic Resonance Imaging (MRI) detectable moiety bound, optionally through a spacer, to a (pseudo)nutrient such as glucose, a natural or unnatural amino acid such as agmatine, or a polyamine such as spermidine BRACCO IMAGING S.P.A. (IT) 2005-08-11 US claimed
EP-1210359-B1 A PROCESS FOR THE PREPARATION OF 3-AMINO BILE ACID DERIVATIVES BRACCO IMAGING SPA (IT) 2005-05-11 EP claimed
US-20050008573-A1 Peptides conjugates, their derivatives with metal complexes and use thereof for magnetic resonance imaging (mri) BRACCO IMAGING S.P.A. (IT) 2005-01-13 US claimed
EP-1369134-A1 New agents for magnetic imaging method Bracco Imaging S.p.A. (IT) 2003-12-10 EP claimed
US-20030109491-A1 Use of heparinoid derivatives for the treatment and diagnosis of disorders which can be treated with heparinoids SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2003-06-12 US claimed
US-20020019549-A1 Bile acid salts BRACCO INTERNATIONAL B.V. 2002-02-14 US claimed
EP-0743283-B1 Recovery of gadolinium and its complexing agents from aqueous solutions containing their complexes BRACCO IMAGING SPA (IT) 2001-06-27 EP claimed
US-5595714-A Recovery of gadolinium and its complexing agents from aqueous solutions containing their complexes DIBRA S.P.A. (IT) 1997-01-21 US claimed
EP-0743283-A2 Recovery of gadolinium and its complexing agents from aqueous solutions containing their complexes BRACCO S.p.A. (IT) 1996-11-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11110185-B2 Combination formulation SLC10A1, SLC10A2, RXFP2 MAOB 590/4885SLC1A1 1841/4885FOLH1 675/4885
US-20030109491-A1 Use of heparinoid derivatives for the treatment and diagnosis of disorders which can be treated with heparinoids SERPINC1, SSB, ADAMTS13 MAOB 1626/4885SLC1A1 3253/4885FOLH1 2087/4885
US-20020019549-A1 Bile acid salts NR1H4, SLC10A1, SLC10A2 MAOB 1770/4885SLC1A1 1043/4885FOLH1 909/4885
US-20050175543-A1 Distinguish between tumor cells and normal cells using novel contrast agents that contain a Magnetic Resonance Imaging (MRI) detectable moiety bound, optionally through a spacer, to a (pseudo)nutrient such as glucose, a natural or unnatural amino acid such as agmatine, or a polyamine such as spermidine SLC7A5, SLC2A9, SLC2A1 MAOB 4475/4885SLC1A1 34/4885FOLH1 235/4885
US-20190247551-A1 SURFACE-MODIFIED POLYMERIC SUBSTRATES GRAFTED WITH A PROPERTIES-IMPARTING COMPOUND USING CLIP CHEMISTRY CLASP1, MACF1, MICA MAOB 853/4885SLC1A1 3554/4885FOLH1 1269/4885
US-11383008-B2 Surface-modified polymeric substrates grafted with a properties-imparting compound using clip chemistry CLASP1, MACF1, MICA MAOB 853/4885SLC1A1 3554/4885FOLH1 1269/4885
US-20050008573-A1 Peptides conjugates, their derivatives with metal complexes and use thereof for magnetic resonance imaging (mri) CCKAR, SSTR3, SSTR1 MAOB 3276/4885SLC1A1 200/4885FOLH1 336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.