Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 8/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | EYA2 | O00167 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29406971 | 0.95 | MAOB (0.42) | SLC1A1MAOBFOLH1CA1CA2 | |
| SCHEMBL4938839 | 0.95 | MAOB (0.42) | SLC1A1MAOBFOLH1CA1CA2 | |
| SCHEMBL1144138 | 0.95 | MAOB (0.42) | SLC1A1MAOBFOLH1CA1CA2 | |
| SCHEMBL8068462 | 0.93 | MAOB (0.43) | SLC1A1MAOBFOLH1CA1CA2 | |
| SCHEMBL8059292 | 0.93 | MAOB (0.43) | SLC1A1MAOBFOLH1CA1CA2 | |
| SCHEMBL8068485 | 0.93 | MAOB (0.43) | SLC1A1MAOBFOLH1CA1CA2 | |
| SCHEMBL7594884 | 0.90 | SLC1A1 (0.47) | SLC1A1MAOBFOLH1CA1CA2 | |
| SCHEMBL6443574 | 0.89 | FOLH1 (0.46) | SLC1A1MAOBFOLH1CA1CA2 | |
| SCHEMBL29742385 | 0.88 | MAOB (0.42) | SLC1A1MAOBFOLH1CA1CA2 | |
| SCHEMBL6443585 | 0.86 | MAOB (0.38) | SLC1A1MAOBFOLH1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822180-B1 | Chelating compounds, their chelates with paramagnetic metal ions, their preparation and use | BRACCO SPA (IT) | 2000-10-25 | — | — | EP | disclosed |
| US-6099824-A | USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING | DIBRA S.P.A. (IT) | 2000-08-08 | — | — | US | disclosed |
| EP-0822180-A1 | Chelating compounds, their chelates with paramagnetic metal ions, their preparation and use | BRACCO S.p.A. (IT) | 1998-02-04 | — | — | EP | disclosed |