SCHEMBL4940413

SCHEMBL4940413

CCCCc1ccc(N(c2ccc(/C=C/c3ccc(N(c4ccc(CCCC)cc4)c4cccc([S+](C)Cc5ccccc5)c4)cc3)cc2)c2cccc(SCCc3ccccc3)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.33
CDC25B P30305 2/20 0.32
DUSP3 P51452 2/20 0.32
LTB4R Q15722 1/20 0.31
HDAC1 Q13547 1/20 0.30
INSR P06213 1/20 0.30
CNR2 P34972 1/20 0.30
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4940430 0.89 BCHE (0.37) BCHELTB4RHDAC1INSR
SCHEMBL4864686 0.82 INSR (0.37) BCHELTB4RINSRAPP
SCHEMBL3408112 0.82 INSR (0.37) BCHELTB4RINSRAPP
SCHEMBL4940408 0.81 BCHE (0.33) BCHECDC25BDUSP3
Trifluoromethanesulfonic Acid SCHEMBL4869774 0.80 HDAC1 (0.34) CDC25BDUSP3LTB4RHDAC1CNR2
SCHEMBL4941173 0.78
SCHEMBL4862718 0.76 CYP3A4 (0.36)
SCHEMBL4862712 0.76 CYP3A4 (0.36)
SCHEMBL3375843 0.75 BCHE (0.40) BCHECNR2
SCHEMBL3373785 0.74 KCNH2 (0.35) BCHELTB4RCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1390664-A4 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES UNIV ARIZONA (US) 2008-01-02 EP disclosed
EP-1390664-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES The Arizona Board of Regents (US) 2004-02-25 EP disclosed
WO-2002079691-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2002-10-10 WO disclosed