Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 3/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408112 | 1.00 | INSR (0.37) | INSRBCHESLC6A4LTB4RAPP | |
| SCHEMBL3375843 | 0.93 | BCHE (0.40) | BCHESLC6A4KCNH2CHRM2HTR1A | |
| SCHEMBL4940430 | 0.92 | BCHE (0.37) | INSRBCHESLC6A4LTB4RKCNH2 | |
| SCHEMBL3373785 | 0.91 | KCNH2 (0.35) | BCHESLC6A4LTB4RKCNH2CHRM2 | |
| SCHEMBL4862718 | 0.84 | CYP3A4 (0.36) | KDM4AKDM2A | |
| SCHEMBL4862712 | 0.84 | CYP3A4 (0.36) | KDM4AKDM2A | |
| SCHEMBL4940413 | 0.82 | BCHE (0.33) | INSRBCHELTB4RAPP | |
| Trifluoromethanesulfonic Acid SCHEMBL4869774 | 0.82 | HDAC1 (0.34) | LTB4RCYSLTR2CYSLTR1TRPA1TRPM2 | |
| SCHEMBL18101186 | 0.80 | RELA (0.50) | INSRBCHESLC6A4KCNH2CHRM2 | |
| SCHEMBL3372867 | 0.80 | MAOA (0.47) | SLC6A4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459106-B2 | Materials, methods, and uses for photochemical generation of acids and/or radical species | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2008-12-02 | — | — | US | disclosed |
| US-20050173683-A1 | Materials, methods, and uses for photochemical generation of acids and/or radical species | THE ARIZ BD OF REGENTS ON BEHALF OF THE UNIV OF AZ (US) | 2005-08-11 | — | — | US | disclosed |