Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | C1R | P00736 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943121 | 0.59 | SMN1; SMN2 (0.35) | LMNAMAPK1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4940386 | 0.58 | TSHR (0.46) | POLBTSHRCYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL4941118 | 0.58 | — | — | |
| SCHEMBL8975997 | 0.57 | KMT2A (0.43) | TSHRLMNACYP2C19MAPK1SMN1; SMN2 | |
| SCHEMBL8157279 | 0.56 | TDP1 (0.67) | ALDH1A1MAPT | |
| SCHEMBL15509416 | 0.56 | POLB (0.58) | POLBLMNAMAPK1ALDH1A1MAPT | |
| SCHEMBL4406145 | 0.55 | KDM4E (0.47) | POLBTSHRGLALMNACYP3A4 | |
| SCHEMBL22734548 | 0.55 | GAA (0.49) | POLBTSHRCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL15829877 | 0.55 | HTR2A (0.44) | POLBLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL18331595 | 0.54 | CTSB (0.42) | ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796037-B2 | Method of detection, separation and identification for expressed trace protein/peptide | IMAI KAZUHIRO (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20080280316-A1 | Mass spectrometry; liquid chromatography; automatic fractionation | IMAI KAZUHIRO | 2008-11-13 | — | — | US | disclosed |