SCHEMBL4943121

SCHEMBL4943121

Fc1cccc2n[se]nc12

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.35
ALDH1A1 P00352 3/20 0.35
GAA P10253 3/20 0.35
KDM4E B2RXH2 3/20 0.35
NPC1 O15118 3/20 0.35
LMNA P02545 3/20 0.35
RAB9A P51151 3/20 0.35
MAPT P10636 3/20 0.35
MEN1 O00255 2/20 0.35
HPGD P15428 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPK1 P28482 1/20 0.35
PRNP P04156 1/20 0.33
PARP1 P09874 3/20 0.32
TDP1 Q9NUW8 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22443280 0.73 CYP1A2 (0.35) ALDH1A1GAALMNAMAPTMEN1
SCHEMBL766609 0.68
SCHEMBL28910018 0.65 MAPT (0.56) SMN1; SMN2ALDH1A1GAAKDM4ENPC1
SCHEMBL12502833 0.65 KDM4E (0.54) SMN1; SMN2ALDH1A1GAAKDM4ENPC1
SCHEMBL3424124 0.64 KDM4E (0.57) SMN1; SMN2ALDH1A1GAAKDM4ENPC1
SCHEMBL16523232 0.64 KEAP1 (0.52) SMN1; SMN2ALDH1A1GAAKDM4ENPC1
SCHEMBL6390857 0.64 KMT2A (0.46) ALDH1A1GAALMNAMAPTMEN1
SCHEMBL31400001 0.62 TDP1 (0.52) SMN1; SMN2ALDH1A1GAAKDM4ENPC1
SCHEMBL14734397 0.62 MAPT (0.44) SMN1; SMN2ALDH1A1GAAKDM4ENPC1
SCHEMBL30659162 0.61 PARP1 (0.34) SMN1; SMN2ALDH1A1GAAKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3947568-B1 SMALL TUNABLE FLUOROPHORES FOR THE DETECTION AND IMAGING OF BIOMOLECULES UNIV COURT UNIV OF EDINBURGH (GB) 2026-04-29 EP disclosed
US-12415926-B2 Small tunable fluorophores for the detection and imaging of biomolecules THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2025-09-16 US disclosed
US-20220154003-A1 SMALL TUNABLE FLUOROPHORES FOR THE DETECTION AND IMAGING OF BIOMOLECULES THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2022-05-19 US disclosed
EP-3947568-A1 SMALL TUNABLE FLUOROPHORES FOR THE DETECTION AND IMAGING OF BIOMOLECULES The University Court Of The University Of Edinburgh (GB) 2022-02-09 EP disclosed
WO-2020187919-A1 SMALL TUNABLE FLUOROPHORES FOR THE DETECTION AND IMAGING OF BIOMOLECULES THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2020-09-24 WO disclosed
EP-1705482-B1 METHOD OF DETECTION, SEPARATION AND IDENTIFICATION FOR EXPRESSED TRACE PROTEIN/PEPTIDE IMAI KAZUHIRO (JP) 2017-09-27 EP disclosed
US-8796037-B2 Method of detection, separation and identification for expressed trace protein/peptide IMAI KAZUHIRO (JP) 2014-08-05 US disclosed
US-20080280316-A1 Mass spectrometry; liquid chromatography; automatic fractionation IMAI KAZUHIRO 2008-11-13 US disclosed
EP-1705482-A2 METHOD OF DETECTION, SEPARATION AND IDENTIFICATION FOR EXPRESSED TRACE PROTEIN/PEPTIDE Imai, Kazuhiro (JP) 2006-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12415926-B2 Small tunable fluorophores for the detection and imaging of biomolecules SCLY, TST, TSHR SMN1; SMN2 4030/4885ALDH1A1 2009/4885GAA 4866/4885
US-20220154003-A1 SMALL TUNABLE FLUOROPHORES FOR THE DETECTION AND IMAGING OF BIOMOLECULES SCLY, TST, TSHR SMN1; SMN2 4030/4885ALDH1A1 2009/4885GAA 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.